(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE Chemical Properties

Boiling point:

50 °C5 mm Hg(lit.)

alpha 

-31o (C=4 IN CHLOROFORM)

Density 

1.189 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.423(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,2-8°C

solubility 

Chloroform (Sparingly)

form 

clear liquid

color 

Colorless to Light yellow

Specific Gravity

1.19

optical activity

[α]20/D 31°, c = 4 in chloroform

BRN 

1722943

Stability:

Hygroscopic, Moisture sensitive

CAS DataBase Reference

36394-75-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

34-43-22

Safety Statements 

26-36/37/39-45-23

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

F 

10-21

HazardClass 

8

PackingGroup 

III

HS Code 

2918199890

MSDS

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(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE Usage And Synthesis

Uses

Frequently used chiral building block. Also used to resolve a bicyclic α-hydroxylactone and to prepare chiral phosphonates used in an enantiomeric excess assay of unprotected amino acids. Useful chiral derivatizing agent.

Purification Methods

It is moisture sensitive and is hydrolysed to the corresponding acid. Check the IR spectrum. If the OH band above 3000cm -1 is too large and broad then the mixture should be refluxed with pure acetyl chloride for 1hour, evaporated and distilled under reduced pressure. [Julia & Sans J Chromatographic Sci 17 651 1979, Dolittle & Heath J Org Chem 49 5041 1984, Beilstein 3 II 189.]

(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE(36394-75-9)Related Product Information

• Sodium percarbonate
• Propionyl chloride
• (S)-(-)-2-ACETOXYPROPIONIC ACID
• 5-ACETOXYPROPIONYL CHLORIDE
• (S)-(-)-2-ACETOXYPROPIONYL CHLORIDE
• (-)-Camphanic acid chloride
• 1-Chlorocarbonyl-1-methylethyl acetate
• Acetoxyacetyl chloride
• Methoxyacetyl chloride
• (+)-CAMPHANIC ACID CHLORIDE