NSC306665 Chemical Properties

Melting point:

172-175℃

Boiling point:

351.3±52.0 °C(Predicted)

Density 

1.373±0.06 g/cm3(Predicted)

solubility 

DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml; Ethanol: 0.25 mg/ml

form 

A crystalline solid

pka

12.02±0.29(Predicted)

InChI

1S/C6H7N3S/c7-5-2-1-4(3-9-5)6(8)10/h1-3H,(H2,7,9)(H2,8,10)

InChIKey

LCKBJNNMWMUYAB-UHFFFAOYSA-N

SMILES

NC(=S)c1ccc(N)nc1

Safety Information

Hazard Codes 

T

Risk Statements 

25-41-43

Safety Statements 

26-36/37/39

RIDADR 

UN 2811 6.1 / PGIII

WGK Germany 

3

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 3 Oral
Eye Dam. 1
Skin Sens. 1

NSC306665 Usage And Synthesis

Description

2-amino Pyridyl-5-thioamide is a synthetic intermediate useful for pharmaceutical synthesis.

Uses

6-Aminopyridine-3-thioamide is a compound with anti-tumor activity that can inhibit the activity of specific enzymes, thereby affecting cell proliferation and survival. 6-Aminopyridine-3-thioamide has also been studied for the inhibition of neurodegenerative diseases and has shown the potential to improve neurological function. The structural characteristics of 6-Aminopyridine-3-thioamide make it an important bioactive molecule in compound development.

References

[1] Perylene bisimide dyes as versatile building blocks for functional supramolecular architectures
[2] Variable temperature film and contact resistance measurements on operating n-channel organic thin film transistors
[3] Perylenediimide nanowires and their use in fabricating field-effect transistors and complementary inverters
[4] Investigation of the spectral, optical and surface morphology properties of the N, N-Dipentyl-3, 4, 9, 10-perylenedicarboximide small molecule for optoelectronic applicationsGunduz BPolymers For Advanced Technologies2016
[5] Sensing properties of the n, n-dipentyl-3, 4, 9, 10-perylenedicarboximide small molecule for different concentrations and solvents for sensor applicationsGunduz BSensor Letters2015
[6] Study of structural, optical properties and electronic structure of PTCDI-C5 organic nanostructureKurban M and Gunduz BChemical Physics Letters2018