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(1R,3S)-Benazepril Hydrochloride

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(1R,3S)-Benazepril Hydrochloride Basic information

Product Name:
(1R,3S)-Benazepril Hydrochloride
Synonyms:
  • 1H-1-Benzazepine-1-acetic acid, 3-[[(1R)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, (3S)-
  • 1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, [S-(R*,S*)]-
  • 2-((S)-3-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)aceticacidhydrochloride
  • (1R,3S)-Benazepril Hydrochloride
  • Benner Pury hydrochloride
  • Benazepril USP RC B
  • Benazepril Related CoMpound B
  • Benazepril USP Related Compound B
CAS:
86541-77-7
MF:
C24H28N2O5HCl
MW:
460.96
Product Categories:
  • API intermediates
Mol File:
86541-77-7.mol
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(1R,3S)-Benazepril Hydrochloride Chemical Properties

Melting point:
181-183 °C(Solv: 2-butanone (78-93-3))
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Safety Information

HS Code 
2933790002
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(1R,3S)-Benazepril Hydrochloride Usage And Synthesis

Uses

(1R,3S)-Benazepril Hydrochloride is an isomer of Benazepril (B119750), an angiotensin converting enzyme inhibitor and a antihypertensive agent.

General Description

Benazepril hydrochloride,(3S)-3-[[(1S)-1-carbethoxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid 3-ethylester hydrochloride (Lotensin), is metabolized rapidly to theactive diacid benazaprilat. As with the ACE prodrugs, nomutagenicity has been found, even though these drugs crossthe placenta.

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