buddlejasaponin IV
buddlejasaponin IV Basic information
- Product Name:
- buddlejasaponin IV
- Synonyms:
-
- buddlejasaponin IV
- [(4R)-13,28-Epoxy-16β,23-dihydroxyolean-11-en-3β-yl]2-O,3-O-bis(β-D-glucopyranosyl)-6-deoxy-β-D-galactopyranoside
- [(4R)-16β,23-Dihydroxy-13,28-epoxyoleana-11-ene-3β-yl]6-deoxy-2-O,3-O-bis(β-D-glucopyranosyl)-β-D-galactopyranoside
- Saikosaponin 1
- Buddleoglucoside IV
- β-D-Galactopyranoside, (3β,4α,16β)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-6-deoxy-
- CAS:
- 139523-30-1
- MF:
- C48H78O18
- MW:
- 943.12
- Mol File:
- 139523-30-1.mol
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buddlejasaponin IV Chemical Properties
- Melting point:
- 288-290℃
- Density
- 1.43±0.1 g/cm3 (20 ºC 760 Torr)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder
- color
- White
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buddlejasaponin IV Usage And Synthesis
Uses
Buddlejasaponin IV (BS‐IV) exerts anti-inflammatory and cytotoxic effects against cancer cells[1].
target
P21 | Chk | Akt | PARP | Caspase | Bcl-2/Bax | p53 | NOS | COX | IL Receptor | TNF-α | NF-kB | MAPK
References
[1] Young Sun Hwang, et al. Buddlejasaponin IV induces cell cycle arrest at G2/M phase and apoptosis in immortalized human oral keratinocytes. Phytother Res. 2011 Oct;25(10):1503-10. DOI:10.1002/ptr.3406
[2] Jong-Heon Won, et al. Anti-inflammatory effect of buddlejasaponin IV through the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via the NF-kappaB inactivation. Br J Pharmacol. 2006 May;148(2):216-25. DOI:10.1038/sj.bjp.0706718
buddlejasaponin IVSupplier
Shanghai Tauto Biotech Co., Ltd.
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- 021-51320588
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Shanghai Aspire Biological Technology Co., Ltd.
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- 021-61317773
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Wuhan ChemFaces Biochemical Co., Ltd.
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- 18607101326 15172504745
- aileen@chemfaces.com
EMMX Biotechnology LLC
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- 888-539-0666
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Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
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buddlejasaponin IV(139523-30-1)Related Product Information
- WITHANOLIDE A(P)
- WITHANOLIDE B(P)(NEW)
- CURINE
- 7,8-Dihydroxycoumarin
- CLINODISIDE A
- Sylvestroside I
- 3-[[2-O-(α-L-Rhamnopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid
- Akebia saponin D
- 4'-O-Acetyl-akebia saponin D
- Dipsanoside A
- Pennogenin 3-O-alpha-L-rhamnopyranosyl-(1-2)-beta-D-xylopyranosyl-(1-4)-beta-D-glucopyranoside
- Dipsanoside B
- (3beta,25R)-14-Hydroxyspirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-xylopyranosyl-(1-4)]-beta-D-glucopyranoside
- oleanolic acid-3-O-β-D-glucopyranosyl (1→2)-α-L-arabinopyranoside
- dipsacoside B