4-O-methylbutein Chemical Properties

Melting point:

198.5-200.5℃

Boiling point:

555.6±50.0 °C(Predicted)

Density 

1.369±0.06 g/cm3(Predicted)

pka

7.33±0.35(Predicted)

InChI

InChI=1S/C16H14O5/c1-21-16-7-3-10(8-15(16)20)2-6-13(18)12-5-4-11(17)9-14(12)19/h2-9,17,19-20H,1H3

InChIKey

WGVFVBIJKULVHA-UHFFFAOYSA-N

SMILES

C(C1=CC=C(O)C=C1O)(=O)C=CC1=CC=C(OC)C(O)=C1

4-O-methylbutein Usage And Synthesis

Uses

4-O-Methylbutein is a phenolic glucoside that can be isolated from Elsholtzia ciliata.4-O-Methylbutein exhibits neuroprotective effects against glutamate-induced HT22 cell death with an EC50 of 35.2 μM[1].

Definition

ChEBI: 3,2',4'-Trihydroxy-4-methoxychalcone is a member of chalcones.

References

[1] Seo YH, et al. Chemical Constituents from the Aerial Parts of Elsholtzia ciliata and Their Protective Activities on Glutamate-Induced HT22 Cell Death. J Nat Prod. 2020 Oct 23;83(10):3149-3155. DOI:10.1021/acs.jnatprod.0c00756

4-O-methylbutein(13323-67-6)Related Product Information

• alpha-Cyperone
• alpha-Terpineol
• Hydroxyecdysone
• hydroxygenkwanin
• 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
• Artemether
• MOSLOFLAVONE
• beta-Eudesmol
• (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
• beta-Sitosterol
• 4'-METHOXYCHALCONE
• 4-METHOXYCHALCONE