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epiberberine

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epiberberine Basic information

Product Name:
epiberberine
Synonyms:
  • epiberberine
  • BerbiniuM
  • 11,12-Dihydro-8,9-dimethoxybenzo[a]-1,3-benzodioxolo[4,5-g]quinolizinium
  • Epiberberine Chloride
  • Siberian
  • 8,9-Dimethoxy-11,12-dihydro-[1,3]dioxolo[4,5-h]isoquinolino[2,1-b]isoquinolin-13-ium
CAS:
6873-09-2
MF:
C20H18NO4+
MW:
336.36122
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
6873-09-2.mol
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epiberberine Chemical Properties

Melting point:
260℃
storage temp. 
Amber Vial, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Orange to Dark Orange
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epiberberine Usage And Synthesis

Uses

Epiberberine Chloride, is a natural bioactive alkaloid, an isomer of Berberine (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells.

target

MEK | ERK | AMPK | Akt | Fatty Acid Synthase | Raf | P450 (e.g. CYP17) | LDL | HMG-CoA Reductase | AChE | BACE | ROS

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