Met-enkephalinamide Chemical Properties

Melting point:

142-145 °C

Boiling point:

1066.7±65.0 °C(Predicted)

Density 

1.303±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

pka

9.97±0.15(Predicted)

Sequence

Tyr-Gly-Gly-Phe-Met-NH2

Met-enkephalinamide Usage And Synthesis

Uses

[Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors.

IC 50

δ Opioid Receptor/DOR

References

[1] Stiene-Martin A, et al. Glial growth is regulated by agonists selective for multiple opioid receptor types in vitro. J Neurosci Res. 1991 Aug;29(4):538-48. DOI:10.1002/jnr.490290415
[2] Kennedy C, et al. [Met5]enkephalin acts via delta-opioid receptors to inhibit pelvic nerve-evoked contractions of cat distal colon. Br J Pharmacol. 1987 Oct;92(2):291-8. DOI:10.1111/j.1476-5381.1987.tb11323.x

Met-enkephalinamide(60117-17-1)Related Product Information

• CYT-1010
• MM 54
• H-ALA-ARG-LEU-ASP-VAL-ALA-SER-GLU-PHE-ARG-LYS-LYS-TRP-ASN-LYS-TRP-ALA-LEU-SER-ARG-NH2
• PACAP (1-27), human, ovine, rat (TFA)
• BAY 55-9837
• H-ALA-VAL-SER-GLU-HIS-GLN-LEU-LEU-HIS-ASP-LYS-GLY-LYS-SER-ILE-GLN-ASP-LEU-ARG-ARG-ARG-PHE-PHE-LEU-HIS-HIS-LEU-ILE-ALA-GLU-ILE-HIS-THR-ALA-OH
• LEU-ENKEPHALIN AMIDE
• ALPHA-ENDORPHIN
• Met-enkephalinamide
• BAM-22P
• TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY
• BAM-12P
• MET-ENKEPHALIN-ARG-PHE
• H-TYR-D-ALA-GLY-PHE-MET-NH2
• PEPTIDE E
• AC-DELTA-ENDORPHIN (HUMAN)
• ADRENORPHIN
• H-TYR-GLY-GLY-PHE-MET-ARG-OH ACOH