Basic information Safety Supplier Related

RUBRATOXINA

Basic information Safety Supplier Related

RUBRATOXINA Basic information

Product Name:
RUBRATOXINA
Synonyms:
  • RUBRATOXINA
  • 10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione
  • 9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride
  • 1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel-
CAS:
22467-31-8
MF:
C26H32O11
MW:
520.528
Mol File:
22467-31-8.mol
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RUBRATOXINA Chemical Properties

Melting point:
210-214℃ (decomposition)
storage temp. 
Store at -20°C
solubility 
Acetonitrile: soluble; DMSO: soluble
form 
A powder
color 
White
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Safety Information

Hazardous Substances Data
22467-31-8(Hazardous Substances Data)
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RUBRATOXINA Usage And Synthesis

Description

Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 μM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.

Uses

Rubratoxin A is a potent and selective competitive PP2A inhibitor.

storage

-20°C

RUBRATOXINASupplier

Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Email
tauto@tautobiotech.com
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Email
sales@chemegen.com
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com