RUBRATOXINA
RUBRATOXINA Basic information
- Product Name:
- RUBRATOXINA
- Synonyms:
-
- RUBRATOXINA
- 10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione
- 9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride
- 1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel-
- CAS:
- 22467-31-8
- MF:
- C26H32O11
- MW:
- 520.528
- Mol File:
- 22467-31-8.mol
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RUBRATOXINA Chemical Properties
- Melting point:
- 210-214℃ (decomposition)
- storage temp.
- Store at -20°C
- solubility
- Acetonitrile: soluble; DMSO: soluble
- form
- A powder
- color
- White
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Safety Information
- Hazardous Substances Data
- 22467-31-8(Hazardous Substances Data)
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RUBRATOXINA Usage And Synthesis
Description
Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 μM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.
Uses
Rubratoxin A is a potent and selective competitive PP2A inhibitor.
storage
-20°C
RUBRATOXINASupplier
Shanghai Tauto Biotech Co., Ltd.
- Tel
- 021-51320588
- tauto@tautobiotech.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai Hongye Biotechnology Co. Ltd
- Tel
- 400-9205774
- sales@glpbio.cn
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
- Tel
- 18818260767
- sales@chemegen.com