cilengitide Chemical Properties

Density 

1.41±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

≥29.43 mg/mL in DMSO; ≥22.56 mg/mL in H2O

form 

powder

pka

4.01±0.10(Predicted)

color 

white to beige

Water Solubility 

Soluble to 10 mg/ml in water

cilengitide Usage And Synthesis

Uses

Angiogenesis inhibitor.

Uses

Cilengitide trifluoroacetic acid salt has been used as an inhibitor of integrin αvβ5.

Definition

ChEBI: Cilengitide is an oligopeptide.

Biochem/physiol Actions

It exhibits antitumor activity in glioblastoma multiforme tumors. Integrins are heterodimers of α and β chain. They are transmembrane receptors which are responsible for cell-to-cell and cell-extracellular matrix interactions. They control tumor angiogenesis, invasion and migration.

storage

Store at -20°C

cilengitide(188968-51-6)Related Product Information

• Ganirelix Acetate
• Taltirelin
• Cosyntropin
• VAPREOTIDE
• Cyclooctane
• 1,3,5-Triazine
• DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS*
• Epothilone D
• Isoquinoline
• Bortezomib
• Trametinib
• Carfilzomib
• LY 294002 HYDROCHLORIDE
• CHIR-99021
• AZD-9291
• Cilengitide
• CYCLO(ARG-GLY-ASP-D-PHE-VAL)
• 1,4,7,10,13-PENTAAZACYCLOPENTADECANE