Curzerene
Curzerene Basic information
- Product Name:
- Curzerene
- Synonyms:
-
- Curzerene
- Isofuranogermacrene
- Isogermafurene
- Isogermafuren
- Neocurzerene
- Benzofuran, 6-ethenyl-4,5,6,7-tetrahydro-3,6-dimethyl-5-(1-methylethenyl)-, (5R,6R)-rel-
- CAS:
- 17910-09-7
- MF:
- C15H20O
- MW:
- 216.32
- Mol File:
- 17910-09-7.mol
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Curzerene Chemical Properties
- Boiling point:
- 282.8±40.0℃ (760 Torr)
- Density
- 0.982±0.06 g/cm3 (20 ºC 760 Torr)
- Flash point:
- 117.5±14.2℃
- solubility
- Soluble in chloroform
- form
- liquid
- color
- Yellow oily
- InChI
- InChI=1/C15H20O/c1-6-15(5)8-14-12(11(4)9-16-14)7-13(15)10(2)3/h6,9,13H,1-2,7-8H2,3-5H3/t13-,15+/s3
- InChIKey
- HICAMHOOTMOHPA-MJZDCSSWNA-N
- SMILES
- O1C2C[C@@](C=C)(C)[C@@H](C(C)=C)CC=2C(C)=C1 |&1:3,7,r|
- LogP
- 3.982 (est)
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Curzerene Usage And Synthesis
Chemical Properties
Colorless crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Curcuma zedoaria.
Uses
Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis[1].
References
[1] Wang Y, et al. Cytotoxic and Antitumor Effects of Curzerene from Curcuma longa. Planta Med. 2017 Jan;83(1-02):23-29. DOI:10.1055/s-0042-107083
CurzereneSupplier
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