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Curzerene

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Curzerene Basic information

Product Name:
Curzerene
Synonyms:
  • Curzerene
  • Isofuranogermacrene
  • Isogermafurene
  • Isogermafuren
  • Neocurzerene
  • Benzofuran, 6-ethenyl-4,5,6,7-tetrahydro-3,6-dimethyl-5-(1-methylethenyl)-, (5R,6R)-rel-
CAS:
17910-09-7
MF:
C15H20O
MW:
216.32
Mol File:
17910-09-7.mol
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Curzerene Chemical Properties

Boiling point:
282.8±40.0℃ (760 Torr)
Density 
0.982±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:
117.5±14.2℃
solubility 
Soluble in chloroform
form 
liquid
color 
Yellow oily
InChI
InChI=1/C15H20O/c1-6-15(5)8-14-12(11(4)9-16-14)7-13(15)10(2)3/h6,9,13H,1-2,7-8H2,3-5H3/t13-,15+/s3
InChIKey
HICAMHOOTMOHPA-MJZDCSSWNA-N
SMILES
O1C2C[C@@](C=C)(C)[C@@H](C(C)=C)CC=2C(C)=C1 |&1:3,7,r|
LogP
3.982 (est)
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Curzerene Usage And Synthesis

Chemical Properties

Colorless crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Curcuma zedoaria.

Uses

Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis[1].

References

[1] Wang Y, et al. Cytotoxic and Antitumor Effects of Curzerene from Curcuma longa. Planta Med. 2017 Jan;83(1-02):23-29. DOI:10.1055/s-0042-107083

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