N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT
N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT Basic information
- Product Name:
- N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT
- Synonyms:
-
- L-2-AMINO-(4-(2'-HYDROXYGUANIDINO)BUTYRIC ACID), 2CH3CO2H
- N---Hydroxy-nor-L-arginine
- (S,E)-2-aMino-4-(2-hydroxyguanidino)butanoic acid
- L-2-AMino-4-(2'-hydroxyguanidino)-butyric acid, nor-NOHA, H-Nar(OH)-OH
- N-o-Hydroxy-L-norarginine
- N-omega-Hydroxy-L-norarginine
- L-2-Amino-{4-(2'-hydroxyguanidino)butyric acid diacetate
- nor-NOHA diacetate
- CAS:
- 189302-40-7
- MF:
- C5H12N4O3
- MW:
- 176.17
- Product Categories:
-
- proteins
- Mol File:
- 189302-40-7.mol
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N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT Chemical Properties
- storage temp.
- Store at 0°C
- form
- White to slightly yellowish powder.
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N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT Usage And Synthesis
Chemical Properties
Off-white powder
Definition
ChEBI: Nomega-hydroxy-nor-l-arginine is a L-alpha-amino acid.
General Description
A potent, selective, competitive, and high affinity inhibitor of arginase. Shown to inhibit arginase from rat liver (IC50 = 2 μM) and mouse macrophages (IC50 = 50 μM). Shown to specifically interact with the manganese-cluster of the enzyme active site. Does not function as a substrate or as an inhibitor for NOS. Hence, nor-NOHA may be a useful tool to study the interplays between arginase and NOS.
Biochem/physiol Actions
Primary Targetarginase from rat liver
N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALTSupplier
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