Basic information Safety Supplier Related

2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID

Basic information Safety Supplier Related

2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID Basic information

Product Name:
2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID
Synonyms:
  • 2'-hydroxy-3'-nitro-3-biphenylcarboxylic acid
  • 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid
  • 2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID
  • Eltrombopag o
  • 3-(2-hydroxy-3-nitrophenyl)benzoic acid
  • Eltrombopag olamine Intermediate 2
  • 3’-Nitro-2’-hydroxy[1,1’]-biphenyl-3-carboxylic Acid
  • Eltrombopag Impurity 13
CAS:
376591-95-6
MF:
C13H9NO5
MW:
259.21
Mol File:
376591-95-6.mol
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2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID Chemical Properties

Boiling point:
452.2±40.0 °C(Predicted)
Density 
1.460±0.06 g/cm3(Predicted)
storage temp. 
Room Temperature
solubility 
Tetrahydrofuran; Methanol;
form 
Solid
pka
3.96±0.10(Predicted)
color 
Yellow
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2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID Usage And Synthesis

Uses

3’-Nitro-2’-hydroxy[1,1’]-biphenyl-3-carboxylic Acid is an intermediate used in the synthesis of N-Hydroxy Eltrombopag (H825795), which is a derivative compound of Eltrombopag (508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

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