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Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate

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Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Basic information

Product Name:
Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate
Synonyms:
  • 4,5-Bis(2-methoxyethoxy)-2-nitrobenzoic acid ethyl ester
  • Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate
  • Methyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate
  • Erlotinib interMidiate III
  • Benzoic acid,4,5-bis(2-Methoxyethoxy)-2-nitro-, ethyl ester
  • Erlotinib Impurity 6
  • 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate
  • Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate ###179688-26-7
CAS:
179688-26-7
MF:
C15H21NO8
MW:
343.33
EINECS:
605-866-9
Product Categories:
  • Erlotinib INTERMEDIATES
Mol File:
179688-26-7.mol
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Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Chemical Properties

Boiling point:
467.8±45.0 °C(Predicted)
Density 
1.215
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Ethyl Acetate (Slightly)
form 
Oil
color 
Yellow
CAS DataBase Reference
179688-26-7(CAS DataBase Reference)
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Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Usage And Synthesis

Uses

Ethyl 4,5-Bis(2-methoxyethoxy)-2-nitrobenzoate is used in the syntheses of 4-(indol-3-yl)quinazolines as epidermal growth factor receptor tyrosine kinase inhibitors. It is also used to prepare Erlotinib hydrochloride (E625000), a useful drug in treatment of non-?small-?cell lung cancer.

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