GLUCAGON HYDROCHLORIDE(HUMAN)
GLUCAGON HYDROCHLORIDE(HUMAN) Basic information
- Product Name:
- GLUCAGON HYDROCHLORIDE(HUMAN)
- Synonyms:
-
- Hyperglycemic-glycogenolytic factor
- l-l-alpha-aspartyl-l-seryl-l-arginyl-l-arginyl-l-alanyl-l-glutaminyl-l-alpha-a
- spartyl-l-phenylalanyl-l-valyl-l-glutaminyl-l-tryptophyl-l-leucyl-l-methionyl-
- threonyl-l-seryl-l-alpha-aspartyl-l-tyrosyl-l-seryl-l-lysyl-l-tyrosyl-l-leucy
- GLUCAGON HYDROCHLORIDE(HUMAN)
- glucagon[pig]
- glukagonnovo
- his-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-a
- CAS:
- 9007-92-5
- MF:
- C153H226ClN43O49S
- MW:
- 3519.21
- EINECS:
- 232-708-2
- Product Categories:
-
- Amino Acids & Derivatives
- Peptides
- Mol File:
- 9007-92-5.mol
GLUCAGON HYDROCHLORIDE(HUMAN) Chemical Properties
- storage temp.
- 2-8°C
- solubility
- Methanol (Very Slightly, Heated, Sonicated), Water
- form
- powder
Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- RTECS
- LZ3980000
- F
- 3-10-21
- Hazardous Substances Data
- 9007-92-5(Hazardous Substances Data)
GLUCAGON HYDROCHLORIDE(HUMAN) Usage And Synthesis
Description
GlucaGon, a recombinant DNA product, was developed as a nasal formulation of glucagon for the treatment of insulin-induced hypoglycemia. Glucagon is widely used by insulin dependent diabetic patients as an emergency treatment for severe hypoglycemic reactions. Use of genetically engineered glucagon by both intranasal and intramuscular methods has a similar effect on hepatic glucose production rate as natural glucagon from pancreatic extraction.
Originator
Novo-Nordisk (Denmark)
Uses
Glucagon is a hormone secreted by the pancreas that raises blood glucose levels. Glucagon is released by the pancreas when blood sugar (glucose) levels fall too low. Glucagon causes the liver to convert stored glycogen into glucose thus increasing glucose levels and having the opposite effect of insulin.
Manufacturing Process
The process comprises treating pancreatic gland material having hyperglycemic activity in aqueous solution at pH 3-4 with 3-4 volumes of acetone to precipitate the hyperglycemic activity material, separating the precipitate and dializing the precipitate to remove inorganic salts and dialyzable low molecular weight impurities, and crystallizing the undialyzed hyperglycemic activity material from aqueous glycine buffer.
brand name
GlucaGen
Therapeutic Function
Antidiabetic
GLUCAGON HYDROCHLORIDE(HUMAN)Supplier
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
- Tel
- 021-50135380
- shchemsky@sina.com
- Tel
- 86-21-63210123
- sj_scrc@sinopharm.com
- Tel
- 010-56205725
- waley188@sohu.com
- Tel
- 400-6206333 18521732826;
- market@aladdin-e.com
GLUCAGON HYDROCHLORIDE(HUMAN)(9007-92-5)Related Product Information
- (MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE)
- H-HIS-ASP-GLU-PHE-GLU-ARG-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-NH2
- GLP-1（Glucagon-like peptide-1）(7-36)
- GLP-1
- Glucagon
- GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN
- glucagon-like peptide 1
- L-Threonine, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-2-methylalanyl-L-alanyl-L-arginyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-valyl-L-lysyl-L-tryptophyl-L-leucyl-L-α-glutamy...
- H-MET-NH2 HCL
- L-Threonine hydrochloride
- H-L-METHR-OH HCL
- L-Tryptophanamide hydrochloride
- H-L-MESER-OH HCL
- H-GLY-LEU-MET-NH2 HCL
- D-ASPARTIC ACID ALPHA-AMIDE HYDROCHLORIDE
- H-ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR-OH
- H-MET-ALA-SER-OH
- H-GLN-NH2 HCL