2,5-Dimethylpyridine Chemical Properties

Melting point:

−15 °C(lit.)

Boiling point:

157 °C(lit.)

Density 

0.926 g/mL at 25 °C(lit.)

vapor pressure 

2.4 mm Hg ( 20 °C)

refractive index 

n20/D 1.499(lit.)

Flash point:

118 °F

pka

6.4(at 25℃)

form 

clear liquid

color 

Colorless to Light orange to Yellow

Water Solubility 

77g/L(23 ºC)

Sensitive 

Hygroscopic

LogP

1.708 (est)

CAS DataBase Reference

589-93-5(CAS DataBase Reference)

NIST Chemistry Reference

Pyridine, 2,5-dimethyl-(589-93-5)

EPA Substance Registry System

2,5-Dimethylpyridine (589-93-5)

Safety Information

Hazard Codes 

Xn,F,Xi

Risk Statements 

10-20/21/22-36/37/38

Safety Statements 

16-26-36/37/39-45

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

RTECS 

OK9625000

HazardClass 

3.2

PackingGroup 

III

HS Code 

2933399990

MSDS

• Language:English Provider:2,5-Lutidine
• Language:English Provider:SigmaAldrich

2,5-Dimethylpyridine Usage And Synthesis

Chemical Properties

2,5-Dimethylpyridine is a colorless liquid, it is flammable and stable under recommended storage conditions.

Uses

2,5-Lutidine was used to displace CO from the haem iron.

Synthesis Reference(s)

Tetrahedron Letters, 17, p. 383, 1976 DOI: 10.1016/S0040-4039(00)93738-9

General Description

The FT-IR and FT-Raman spectra of 2,5-lutidine was studied.

Hazard

2,5-Dimethylpyridine is acute toxicity.

Purification Methods

Steam distil the lutidine from a solution containing 1-2 equivalents of 20% H2SO4 until about 10% of the base has been carried over with the non-basic impurities, then the acidic solution is made alkaline, and the base is separated, dried with NaOH and fractionally distilled twice. Dry the distillate with Na and fractionally distil it through a Todd column (p 11) packed with glass helices. The hydrochloride has m 219o(dec), and the picrate has m 170.5o (from EtOH or H2O). [Beilstein 20 H 244, 20 II 160, 20 III/IV 2774, 20/6 V 27.]

2,5-Dimethylpyridine(589-93-5)Related Product Information

• Dimethyl sulfoxide
• N,N-Dimethylformamide
• Dimethyl sulfone
• 2-Chloro-3-cyanopyridine
• Poly(dimethylsiloxane)
• 2,6-Dimethylpyridine 98+%
• Dimethicone
• N,N-Dimethylacetamide
• 2,4-DIMETHYLPYRIDINE(2,4-LUTIDINE)
• a,b-Dimethylpyridine,2,3-DIMETHYLPYRIDINE(2,3-LUTIDINE),2,3-DIMETHYLPYRIDINE
• 2,5-PYRIDINEDICARBOXYLIC ACID
• Pyridoxal hydrochloride
• Nalidixic acid
• Pyridoxine hydrochloride
• Pyridoxamine dihydrochloride
• 6-METHYLNICOTINAMIDE
• Pyridoxal 5'-phosphate monohydrate
• Pyridoxine