FGIN-1-27
FGIN-1-27 Basic information
- Product Name:
- FGIN-1-27
- Synonyms:
-
- FGIN-1-27
- N,N-DIHEXYL-2-(4-FLUOROPHENYL)INDOLE-3-ACETAMIDE
- N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide
- FGIN-1-27,98%
- FGIN-1-27N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide
- 1H-Indole-3-acetamide, 2-(4-fluorophenyl)-N,N-dihexyl-
- indoleacetamide,Inhibitor,inhibit,BBB,FGIN127,blood brain barrier,FGIN 1 27,FGIN 1-27,peripheral benzodiazepine receptor,convulsions,Isoniazid,PBR
- 2-(2-(4-Fluorophenyl)-1H-indol-3-yl)-N,N-dihexylacetamide
- CAS:
- 142720-24-9
- MF:
- C28H37FN2O
- MW:
- 436.6
- Product Categories:
-
- Miscellaneous Enzyme
- Mol File:
- 142720-24-9.mol
More
Less
FGIN-1-27 Chemical Properties
- Melting point:
- 96-97 °C
- Boiling point:
- 608.3±55.0 °C(Predicted)
- Density
- 1.0538 (estimate)
- storage temp.
- 2-8°C
- solubility
- methanol: 20 mg/mL
- form
- White powder.
- pka
- 16.45±0.30(Predicted)
- color
- Off-white to light yellow
More
Less
Safety Information
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29339980
MSDS
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
More
Less
FGIN-1-27 Usage And Synthesis
Chemical Properties
white to off-white powder
Uses
FGIN-1-27 is a potent inositol monophosphatase inhibitor.
Definition
ChEBI: 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide is a phenylindole.
Biological Activity
Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC 50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.
storage
Room temperature
FGIN-1-27Supplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 021-61259108 18621169109
- market03@meryer.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Shandong Xiya Chemical Co., Ltd
- Tel
- 4009903999 13355009207
- 3007715519@qq.com
BOC Sciences
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
More
Less
FGIN-1-27(142720-24-9)Related Product Information
- Flumazenil
- 5-(4-METHOXYPHENYL)PYRROLO[2,1-D][1,5]BENZOTHIAZEPIN-4-OL N,N-DIMETHYLCARBAMATE
- 1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE
- NBD FGIN-1-27 ANALOG
- 5-PHENYLPYRROLO[2,1-D][1,5]-BENZOTHIAZEPIN-4-OL HEXANOATE
- 5-(4-METHOXYPHENYL)PYRROLO[2,1-D][1,5]BENZOTHIAZEPIN-4-OL ACETATE
- 3-HYDROXYMETHYL-BETA-CARBOLINE
- NBD FGIN-1-27 ANALOG
- N,N-DIHEXYL-2-PHENYLINDOLE-3-ACETAMIDE
- 3-methyl-2-phenyl-1H-indole
- 2-(2-PHENYL-1H-INDOL-3-YL)-ETHYLAMINE
- (2-PHENYL-1H-INDOL-3-YL)-ACETALDEHYDE
- N,N-DI-N-HEXYLACETAMIDE
- 6-(4-FLUOROPHENYL)INDOLE
- INDOLE-3-(N,N-DIMETHYL)ACETAMIDE
- FGIN-1-27