4-Bromomethyl-1,2-dihydroquinoline-2-one Chemical Properties

Melting point:

255-258°C

Boiling point:

391.8±42.0 °C(Predicted)

Density 

1.542±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

powder to crystal

pka

11.17±0.70(Predicted)

color 

White to Light yellow to Light orange

InChI

InChI=1S/C10H8BrNO/c11-6-7-5-10(13)12-9-4-2-1-3-8(7)9/h1-5H,6H2,(H,12,13)

InChIKey

BBAHJCUCNVVEQU-UHFFFAOYSA-N

SMILES

N1C2=C(C=CC=C2)C(CBr)=CC1=O

CAS DataBase Reference

4876-10-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-34

Safety Statements 

26-36/37/39-45

Hazard Note 

Irritant

HazardClass 

8

HS Code 

29334900

MSDS

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4-Bromomethyl-1,2-dihydroquinoline-2-one Usage And Synthesis

Chemical Properties

Light yellow to light reddish yellow solid

Uses

4-Bromomethyl-2(1H)-quinolinone is a reagent used in the preparation of coumarins and 1-aza coumarins which has nti-microbial, anti-inflammatory, and analgesic activities.

Application

4-Bromomethyl-1,2-dihydroquinoline-2-one is used as an intermediate in Rebamipide, a gastroprotective agent used in the treatment of gastritis, gastroduodenal ulcers and mucosal protection.

4-Bromomethyl-1,2-dihydroquinoline-2-one(4876-10-2)Related Product Information

• Mesotrione
• 4-methylquinoline
• 4'-Bromoacetophenone
• 4-Bromomethylbenzoic acid
• 4-Methyl-2-pentanone
• 2-Bromoacetophenone
• 6-Hydroxy-2(1H)-3,4-dihydroquinolinone
• Bromopentafluorobenzene
• 1-Bromohexane
• 1-Bromopentane
• Cuprous bromide
• Bromoacetic acid
• (Bromomethyl)cyclopentane
• (Bromomethyl)cyclobutane
• (Bromomethyl)cyclopropane
• Cyclohexylmethyl bromide
• Bromomethyl methyl ether
• 2-Hydroxy-4-methylpyridine