Tris(hydroxymethyl)nitromethane Chemical Properties

Melting point:

160 °C (dec.) (lit.)

Boiling point:

273.1°C (rough estimate)

Density 

1.5652 (rough estimate)

refractive index 

1.4183 (estimate)

solubility 

H2O: soluble220g/100ml at 20°C

pka

12.32±0.10(Predicted)

form 

powder to lump

color 

White to Almost white

Water Solubility 

It is soluble in water.

Merck 

14,9753

BRN 

742427

LogP

0.350 (est)

CAS DataBase Reference

126-11-4(CAS DataBase Reference)

NIST Chemistry Reference

1,3-Propanediol, 2-(hydroxymethyl)-2-nitro-(126-11-4)

EPA Substance Registry System

2-(Hydroxymethyl)-2-nitro-1,3-propanediol (126-11-4)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38-20/21/22

Safety Statements 

26-36

WGK Germany 

3

RTECS 

TY7350000

F 

4.10

TSCA 

Yes

HS Code 

29221990

Hazardous Substances Data

126-11-4(Hazardous Substances Data)

Toxicity

mouse,LD50,intraperitoneal,4gm/kg (4000mg/kg),Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 11(1), Pg. 73, 1977.

MSDS

• Language:English Provider:Tris(hydroxymethyl)nitromethane
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Tris(hydroxymethyl)nitromethane Usage And Synthesis

Chemical Properties

Off-white to orange solid. It crystallizes as white crystals in the mixed solution of ethyl acetate and benzene. Soluble in alcohol, slightly soluble in benzene and other hydrocarbons. Solubility in water (20°C) 220g/100ml.

Uses

Tris(hydroxymethyl)nitromethane, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is used as a primary and secondary intermediate.

Preparation

Tris(hydroxymethyl)nitromethane is prepared by the condensation of nitromethane and formaldehyde under basic conditions.

Application

Tris(hydroxymethyl)nitromethane is a bactericide and slimicide for use in cooling fluids, paper and pulp industry; as a curing agent for certain adhesives; viscositycontrolling agent in cosmetics.To inhibit bacterial growth in circulating industrial water systems, cutting oils, nonprotein glues and sizings.

General Description

Tris(hydroxymethyl)nitromethane undergoes crosslinking with hexamethylene diisocyanate to form monolithic energetic gels. It is an effective hardener for variety of tannin-based adhesives.

Hazard

Moderate fire risk. Irritant to skin and eyes.

Purification Methods

Crystallise it from CHCl3/ethyl acetate or ethyl acetate/*benzene. It is an acid and a 0.1M solution in H2O has pH 4.5. IRRITANT. [Beilstein 1 H 520.]

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