Boc-Thr(Bzl)-OH Chemical Properties

Melting point:

80-82 °C(lit.)

alpha 

22 º (c=2 in 95% ethanol)

Boiling point:

461.5±45.0 °C(Predicted)

Density 

1.152±0.06 g/cm3(Predicted)

refractive index 

16.5 ° (C=1, MeOH)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

pka

3.50±0.10(Predicted)

form 

powder to crystal

color 

White to Almost white

optical activity

[α]20/D +16.5±1°, c = 1% in methanol

BRN 

3065591

InChI

InChI=1S/C16H23NO5/c1-11(21-10-12-8-6-5-7-9-12)13(14(18)19)17-15(20)22-16(2,3)4/h5-9,11,13H,10H2,1-4H3,(H,17,20)(H,18,19)/t11-,13+/m1/s1

InChIKey

CTXPLTPDOISPTE-YPMHNXCESA-N

SMILES

C(O)(=O)[C@H]([C@H](OCC1=CC=CC=C1)C)NC(OC(C)(C)C)=O

CAS DataBase Reference

15260-10-3(CAS DataBase Reference)

EPA Substance Registry System

L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- (15260-10-3)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

TSCA 

Yes

HS Code 

2924 29 70

MSDS

• Language:English Provider:N-tert-Butoxycarbonyl-O-benzyl-L-threonine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Boc-Thr(Bzl)-OH Usage And Synthesis

Chemical Properties

White crystalline

Uses

Boc-O-benzyl-L-threonine, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

Application

Boc-Thr(Bzl)-OH is a standard building block for introduction of threonine amino-acid residues by Boc SPPS.

Boc-Thr(Bzl)-OH(15260-10-3)Related Product Information

• tert-Butyl peroxyacetate
• tert-Butanol
• L-Threonine
• Benzyl chloride
• Benzyl benzoate
• Benzyl alcohol
• Benzyl isocyanate
• Benzyl nicotinate
• Benzyl
• N-tert-Butyloxycarbonyl-N-methyl-O-benzyl-L-threonine
• N-ALPHA-T-BOC-O-BENZYL-D-THREONINE / (2R,3S),N-ALPHA-T-BOC-O-BENZYL-D-THREONINE,BOC-O-BENZYL-D-THREONINE
• Boc-L-Threonine
• BOC-THR(P-CHLORO-BZL)-OH DCHA
• BOC-L-THR(BZL)-O-CH2-PHI-CH2-COOH DCHA
• BOC-O-BENZYL-L-THREONINE N-CARBOXY ANHYDRIDE
• BOC-O-BENZYL-L-THREONINE P-NITROPHENYL ESTER,BOC-O-BENZYL-L-THREONINE 4-NITROPHENYL ESTER
• BOC-THR(BZL)-OSU
• BOC-O-BENZYL-D-THREONINE 4-OXYMETHYLPHENYLACETAMIDOMETHYL RESIN,BOC-O-BENZYL-D-THREONINE MERRIFIELD RESIN