FMOC-GAMMA-ABU-OH Chemical Properties

Melting point:

172.0 to 176.0 °C

Boiling point:

571.9±33.0 °C(Predicted)

Density 

1.256±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

pka

4.68±0.10(Predicted)

form 

Powder

color 

White

Water Solubility 

Slightly soluble in water.

BRN 

7491485

CAS DataBase Reference

116821-47-7(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

2924 29 70

HazardClass 

IRRITANT

MSDS

• Language:English Provider:SigmaAldrich

FMOC-GAMMA-ABU-OH Usage And Synthesis

Description

Fmoc-4-aminobutanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-4-aminobutanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

White powder

Uses

4-(Fmoc-amino)butyric acid is used in agrochemical, pharmaceutical and dyestuff field.

FMOC-GAMMA-ABU-OH(116821-47-7)Related Product Information

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