Cyclamic acid Chemical Properties

Melting point:

~180 °C (dec.)

Boiling point:

332.48℃[at 101 325 Pa]

Density 

1.149 (estimate)

vapor pressure 

0Pa at 25℃

refractive index 

1.5500 (estimate)

storage temp. 

Refrigerator

solubility 

dioxane: soluble1g/10 mL, clear, colorless (hot)

form 

solid

pka

pKa 2.28(H2O t=RT c=0.056) (Uncertain)

color 

White

Water Solubility 

133g/L

Merck 

14,2703

BRN 

2208885

LogP

-1.61 at 25℃

CAS DataBase Reference

100-88-9(CAS DataBase Reference)

NIST Chemistry Reference

N-cyclohexylsulfamic acid(100-88-9)

EPA Substance Registry System

Cyclamic acid (100-88-9)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

2

RTECS 

GV6950000

HS Code 

2929909000

Hazardous Substances Data

100-88-9(Hazardous Substances Data)

Toxicity

mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#01774,

MSDS

• Language:English Provider:SigmaAldrich

Cyclamic acid Usage And Synthesis

Aroma

Practically odorless. Initially sour, then sweet taste (sweet aftertaste).

Chemical Properties

White Solid

Uses

A non-nutritive sweetener.
The sweetness is approximately 30 times that of cane sugar, while the acidity provided by this material is even greater than that derived from an equal weight of Citric acid.
Cyclamic acid is being used on an increasing scale (1966) as a sweet acidifying agent in soft drinks of no nutritional value (diet-soda, lowc.rdorie carbonated beverages, etc.).

Definition

ChEBI: A member of the class of sulfamic acids that is sulfamic acid carrying an N-cyclohexyl substituent.

brand name

Hexamic Acid (Abbott).

General Description

The N-cyclohexylsulfamic acid salts of well?known therapeutic agents were prepared.

Flammability and Explosibility

Not classified

Safety Profile

Suspected human carcinogen producing bladder tumors. Poison by intravenous route. LWdly toxic by ingestion. When heated to decomposition it emits toxic fumes of SOx and NOx.

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