Basic information Safety Supplier Related

3-BROMO-7-NITROINDAZOLE

Basic information Safety Supplier Related

3-BROMO-7-NITROINDAZOLE Basic information

Product Name:
3-BROMO-7-NITROINDAZOLE
Synonyms:
  • 3-BroMo-7-nitro-1H-indazo...
  • 1H-INDAZOLE,3-BROMO-7-NITRO-
  • BRNI
  • 7-NITROINDAZOLE, 3-BROMO-
  • 3-BROMO-7-NITROINDAZOLE
  • 3-BROMO-7-NITRO-1H-INDAZOLE
  • 3-Bromo-7-nitroindazole, 98+%
  • 3-Bromo-7-nitroindaz
CAS:
74209-34-0
MF:
C7H4BrN3O2
MW:
242.03
Product Categories:
  • Nitric Oxide Synthase (iNOS)Enzyme Inhibitors by Enzyme
  • Nitric Oxide Synthase neuronalNitric Oxide and Cell Stress
  • Enzyme Inhibitors by Enzyme
  • L to
  • Nitric Oxide Metabolism
  • Nitric Oxide Synthase RegulatorsCell Signaling Enzymes
  • Indoles and derivatives
  • All Inhibitors
  • Inhibitors
  • Nitric Oxide Reagents
  • NOS Inhibitors
  • Nitric Oxide
Mol File:
74209-34-0.mol
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3-BROMO-7-NITROINDAZOLE Chemical Properties

Melting point:
175-185 °C
Boiling point:
182°C
Density 
1.8856 (rough estimate)
refractive index 
1.6200 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
ethanol: 25 mg/mL
form 
powder
pka
7.85±0.40(Predicted)
color 
light yellow
Sensitive 
Light Sensitive
CAS DataBase Reference
74209-34-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T
Risk Statements 
60
Safety Statements 
53-22-36/37/39-45
WGK Germany 
3
Hazard Note 
Harmful to reproduction
HazardClass 
IRRITANT
HS Code 
2933998090

MSDS

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3-BROMO-7-NITROINDAZOLE Usage And Synthesis

Chemical Properties

Yellow Crystals

Uses

A more potent inhibitor of rat cerebellar nitric oxide synthase than 7-nitroindazole

Uses

Inhibitor of nitric oxide synthase (NOS)

Uses

3-Bromo-7-nitroindazole is a potent and selective neuronal nitric oxide synthase (nNOS) inhibitor (1,2). It is also a neuroprotective compound that inhibits the endoplasmic reticulum stress pathway. 3-Bromo-7-nitroindazole has been used to study the role of nitric oxide synthase (nNOS) in spatial memory formation in rats (2).

storage

Desiccate at +4°C

3-BROMO-7-NITROINDAZOLESupplier

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