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2-(Trifluoromethyl)benzyl bromide

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2-(Trifluoromethyl)benzyl bromide Basic information

Product Name:
2-(Trifluoromethyl)benzyl bromide
Synonyms:
  • ALPHA'-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-XYLENE
  • α′-Bromo-α,α,α-trifluoro-o-xylene
  • 1-(bromomethyl)-2-(trifluoromethyl)benzene
  • à'-bromo-à,à,à-trifluoro-o-xylene
  • 2-(Trifluoromethyl)benzyl bromide 98%
  • 2-(Trifluoromethyl)benzylbromide98%
  • O-(TRIFLUOROMETHYL)BENZYL BROMIDE
  • Benzene, 1-(bromomethyl)-2-(trifluoromethyl)-
CAS:
395-44-8
MF:
C8H6BrF3
MW:
239.03
EINECS:
206-901-7
Product Categories:
  • Fluorine series
  • Benzyl
  • Fluoro-contained benzyl bromide series
Mol File:
395-44-8.mol
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2-(Trifluoromethyl)benzyl bromide Chemical Properties

Melting point:
34-35 °C
Boiling point:
72 °C (7.5 mmHg)
Density 
1.571 g/mL at 25 °C(lit.)
refractive index 
1.496-1.499
Flash point:
83 °C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder to lump to clear liquid
color 
White or Colorless to Light yellow
Specific Gravity
1.571
Sensitive 
Lachrymatory
BRN 
2256977
InChIKey
TXVVVEUSVBLDED-UHFFFAOYSA-N
CAS DataBase Reference
395-44-8(CAS DataBase Reference)
NIST Chemistry Reference
2-Trifluoromethylbenzyl bromide(395-44-8)
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Safety Information

Hazard Codes 
C,Xi
Risk Statements 
34
Safety Statements 
45-36/37/39-25-26
RIDADR 
1760
WGK Germany 
3
Hazard Note 
Corrosive/Lachrymatory
HazardClass 
8
PackingGroup 
III
HS Code 
29039990

MSDS

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2-(Trifluoromethyl)benzyl bromide Usage And Synthesis

Uses

2-(Trifluoromethyl)Benzyl Bromide (cas# 395-44-8) is a useful research chemical.

Chemical Properties

Colorless to light yellow liqui

Uses

2-(Trifluoromethyl)benzyl bromide may be used in chemical synthesis.

Preparation

A solution of 30 ml of phosphorus tribromide in 60 ml of absolute toluene was added dropwise at 20°-30° C. to a solution of 14 g of o-trifluoromethylbenzyl alcohol in 80 ml of absolute toluene. Subsequently, the reaction mixture was stirred at room temperature for 2 hours, the toluene was distilled under reduced pressure, the residue was dissolved in methylene chloride, treated with water and the mixture was adjusted to pH 8.0 with potassium hydrogen carbonate. The aqueous phase was extracted three times with CH2Cl2 and the organic phases were washed twice with water and once with saturated NaCl solution, dried over Na2 SO4 and evaporated under reduced pressure. 2-(Trifluoromethyl)benzyl bromide was obtained as the residue.

2-(Trifluoromethyl)benzyl bromide Preparation Products And Raw materials

Preparation Products

Raw materials

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