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L-Selenomethionine

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L-Selenomethionine Basic information

Product Name:
L-Selenomethionine
Synonyms:
  • (S)-(+)-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID
  • (S)-2-AMINO-4-(METHYLSELENO)BUTYRIC ACID
  • SEMET
  • SELENOMETHIONINE, L-(+)-
  • SELENO-L-METHIONINE
  • L-(+)-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID
  • L-(+)-SELENOMETHIONINE
  • L-SELENOMETHIONINE
CAS:
3211-76-5
MF:
C5H11NO2Se
MW:
196.11
EINECS:
608-705-0
Product Categories:
  • Seleno Amino Acid
  • Methionine [Met, M]
  • Amino Acids
  • Antioxidant
  • Biochemistry
  • Biological-modified Amino Acids
  • Amino Acid Derivatives
  • Classes of Metal Compounds
  • Se (Selenium) Compounds
  • Semimetal Compounds
  • amino acid
  • 3211-76-5
Mol File:
3211-76-5.mol
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L-Selenomethionine Chemical Properties

Melting point:
265 °C
alpha 
18 º (c=1, 1N HCl)
Boiling point:
320.8±37.0 °C(Predicted)
refractive index 
18 ° (C=0.5, 2mol/L HCl)
storage temp. 
-20°C
solubility 
H2O: 50 mg/mL
form 
powder
pka
2.26±0.10(Predicted)
color 
white to off-white
Water Solubility 
soluble
Merck 
14,8441
InChI
InChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChIKey
RJFAYQIBOAGBLC-BYPYZUCNSA-N
SMILES
C(O)(=O)[C@@H](N)CC[Se]C
LogP
0.152 (est)
CAS DataBase Reference
3211-76-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T,N
Risk Statements 
23/25-33-50/53
Safety Statements 
20/21-28-45-60-61-28A
RIDADR 
UN 3283 6.1/PG 2
WGK Germany 
3
RTECS 
EK7713840
10
HazardClass 
6.1
PackingGroup 
III
HS Code 
29309090

MSDS

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L-Selenomethionine Usage And Synthesis

Chemical Properties

Solid

Uses

A compound shown to increase expression of glutathione peroxidase

Uses

Seleno-L-methionine has been used:

  • in toxicity studies in Japanese Medaka embryos
  • to study its effects on selenium status indicators in pregnant long-tailed macaques (Macaca Fascicularis)
  • to label proteins for single wavelength anomalous dispersion (SAD) phasing

Definition

ChEBI: The L-enantiomer of selenomethionine.

General Description

Seleno-L-Methionine (SeMet), an organic form of selenium is found in Cupriavidus metallidurans.

Biochem/physiol Actions

Seleno-L-Methionine (SeMet) is capable of repressing atopic dermatitis (AD)-like skin lesions. It can also prevent the expression of total immunoglobulin E (IgE) and interleukin 4 (IL-4). It can cause ecotoxicity as it is absorbed by fish through diet.

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