2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE LITHIUM SALT Chemical Properties

storage temp. 

−20°C

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

10-21

MSDS

• Language:English Provider:SigmaAldrich

2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE LITHIUM SALT Usage And Synthesis

Uses

ddCTP trilithium is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddCTP trilithium is a nucleoside analog that targets the reverse trsanscriptase of human immunodeficiency virus (HIV). ddCTP trilithium can be used for AIDS research[1][2].

References

[1] Z G Chidgeavadze, et al. 3'-Fluoro-2',3'-dideoxyribonucleoside 5'-triphosphates: terminators of DNA synthesis. FEBS Lett. 1985 Apr 22;183(2):275-8. DOI:10.1016/0014-5793(85)80792-4
[2] Pelletier H, et al. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science. 1994 Jun 24;264(5167):1891-903. PMID:7516580

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