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D(+)-Ribonic acid gamma-lactone

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D(+)-Ribonic acid gamma-lactone Basic information

Product Name:
D(+)-Ribonic acid gamma-lactone
Synonyms:
  • D-RIBOSE-LACTONE
  • D-(+)-RIBONIC ACID GAMMA-LACTON
  • D(+)-RIBONIC ACID GAMMA-LACTONE
  • D-(+)-RIBONIC ACID G-LACTONE
  • D-(+)-RIBONIC GAMMA-LACTONE
  • D(+)-RIBONO-1,4-LACTONE
  • D-RIBONO-1,4-LACTONE
  • D-(+)-RIBONO-GAMMA-LACTONE
CAS:
5336-08-3
MF:
C5H8O5
MW:
148.11
EINECS:
226-256-5
Product Categories:
  • Inhibitors
  • 13C & 2H Sugars
  • Biochemistry
  • Ribose
  • Sugar Acids
  • Sugars
  • Sugars, Carbohydrates & Glucosides
  • Dextrins、Sugar & Carbohydrates
  • Carbohydrates & Derivatives
Mol File:
5336-08-3.mol
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D(+)-Ribonic acid gamma-lactone Chemical Properties

Melting point:
85-87 °C(lit.)
alpha 
18 º (c=5, H2O)
Boiling point:
188.68°C (rough estimate)
Density 
1.2336 (rough estimate)
refractive index 
18 ° (C=1, H2O)
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: 0.1 g/mL, clear
form 
Powder
pka
12.10±0.60(Predicted)
color 
White to Pale Yellow
optical activity
[α]24/D +18°, c = 1 in H2O
Water Solubility 
soluble
BRN 
82057
Stability:
Stable
CAS DataBase Reference
5336-08-3(CAS DataBase Reference)
NIST Chemistry Reference
D-(+)-Ribonic acid gamma-lactone(5336-08-3)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29322090

MSDS

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D(+)-Ribonic acid gamma-lactone Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

D-ribono-1,4-lactone is a compound useful in organic synthesis.

Uses

A sugar lactone as inhibitor of β-galactosidase of E. coli.

Uses

Important chiral synthon

Definition

ChEBI: A five-membered form of ribonolactone having D-configuration.

Purification Methods

Purify D-(+)-ribonic acid--lactone by recrystallisation from EtOAc. The tribenzoate has m 54-56o (from AcOH), [] D 25 +27o (c 2.37, Me2NCHO), and the 3,5-O-benzylidene derivative has m 230-231.5o (needles from Me2CO-pet ether) and [] D 25 -177o (CHCl3). [Chen & Joulié J Org Chem 49 2168 1984, Zinner & Voigt J Carbohydr Research 7 38 1968.]

D(+)-Ribonic acid gamma-lactone Preparation Products And Raw materials

Raw materials

Preparation Products

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