4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN Chemical Properties

Melting point:

212-216 °C(lit.)

Density 

1.6176 (rough estimate)

refractive index 

1.4490 (estimate)

storage temp. 

Inert atmosphere,2-8°C

solubility 

Soluble in acetonitrile, dichloromethane, N,N-dimethylformamide, methanol

form 

Powder

color 

Yellow crystals or powder

Water Solubility 

Insoluble in water.

λmax

348 nm (MeOH)

BRN 

4750487

Major Application

Electrostatic imaging process; resists; printed circuit boards; semiconductor devices

Biological Applications

Analyzing bile acid; anticancer agents; identifying bacteria; identifying/measuring lauric acid metabolites; measuring cyclosporine; studying/monitoring early stages of protein folding;treating gastrointestinal diseases; derivatization reagent for carboxylic acids; as a substrate for measuring lauric acid hydroxylase activity

CAS DataBase Reference

88404-25-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,C

Risk Statements 

22-36/37/38

Safety Statements 

26

RIDADR 

1759

WGK Germany 

3

F 

21

Hazard Note 

Corrosive

HazardClass 

8

PackingGroup 

III

HS Code 

29322090

MSDS

• Language:English Provider:SigmaAldrich

4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN Usage And Synthesis

Chemical Properties

Light Greenish-Yellow Powder

Uses

A fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids

Uses

4-Bromomethyl-6,7-dimethoxycoumarin is used as fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids. It is also used as derivatization reagent: for quantitation of clofibric, bezafibric and fenofibric acids in liver by liquid chromatography, in determination of the concentration of tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry and for determination of carboxylic acids in chromatographic detection.

Uses

4-Bromomethyl-6,7-dimethoxycoumarin was used as fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids. It was also used as derivatization reagent:

• for quantitation of clofibric, bezafibric and fenofibric acids in liver by liquid chromatography
• in determination of the concentration of tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
• for determination of carboxylic acids in chromatographic detection

4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN(88404-25-5)Related Product Information

• 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN
• 3,4-DIMETHOXYSTYRENE
• 6,7-DIMETHOXY-4-METHYLCOUMARIN
• 6-Hydroxycoumarin
• 3-Bromo-2-methylpropene
• 2-Methoxyhydroquinone
• 4-METHYLESCULETIN
• 4-Bromomethyl-7-methoxycoumarin
• 6-HYDROXY-4-METHYLCOUMARIN
• 4-METHOXYPHENETHYL BROMIDE
• SCOPARONE
• Allyl bromide
• 7-Methoxy-4-methylcoumarin
• 3-Hydroxyphenyl acetate
• 2,4-Dimethoxyphenol
• Scopoletin
• Methyl 4-bromocrotonate
• Esculetin