2,4-Dichloronitrobenzene Chemical Properties

Melting point:

29-32 °C(lit.)

Boiling point:

258 °C(lit.)

Density 

1.479

vapor pressure 

0.013 hPa (20 °C)

refractive index 

1.5512 (estimate)

Flash point:

>230 °F

storage temp. 

Store below +30°C.

solubility 

188g/l

form 

Crystalline Low Melting Solid

color 

Yellow-brown

Water Solubility 

188 mg/L (20 ºC)

BRN 

1451655

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.

CAS DataBase Reference

611-06-3(CAS DataBase Reference)

IARC

2B (Vol. 123) 2020

NIST Chemistry Reference

Benzene, 2,4-dichloro-1-nitro-(611-06-3)

EPA Substance Registry System

2,4-Dichloronitrobenzene (611-06-3)

Safety Information

Hazard Codes 

Xi,N,Xn

Risk Statements 

36/37/38-51/53-43-21/22

Safety Statements 

26-36-61-36/37-24

RIDADR 

2811

WGK Germany 

3

RTECS 

CZ5420000

Autoignition Temperature

500 °C

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29049085

Hazardous Substances Data

611-06-3(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 380 mg/kg LD50 dermal Rat 920 mg/kg

MSDS

• Language:English Provider:1,3-Dichloro-4-nitrobenzene
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,4-Dichloronitrobenzene Usage And Synthesis

Chemical Properties

yellow crystals

Uses

2,4-Dichloro-1-nitrobenzene is used as a reagent in the synthesis of the hepatitis C virus polymerase inhibitor, Deleobuvir (BI 207127).

Production Methods

1,3-Dichlorobenzene is nitrated with mixed acid, and the product 2,4-Dichloronitrobenzene is separated from the resulting isomer mixture.

General Description

Light yellow needles or amber crystalline solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Can react vigorously with oxidizing materials.

Fire Hazard

2,4-Dichloronitrobenzene is combustible.

2,4-Dichloronitrobenzene(611-06-3)Related Product Information

• 2',4'-Dichloroacetophenone
• 1-Chloro-3-nitrobenzene
• Sodium 3-nitrobenzenesulphonate
• 4-Nitrobenzoic acid
• 2,6-DICHLORO-3-NITROTOLUENE
• 1,2,4-Trichloro-5-nitrobenzene
• 2,4,6-TRICHLORONITROBENZENE
• 2,4-DICHLORO-3,5-DINITROBENZOIC ACID
• 2,4-Dichloro-5-nitrobenzotrifluoride
• 2,6-DICHLORO-3-NITROBENZONITRILE
• 2,4-Dichloronitrobenzene
• 2,6-Dichloronitrobenzene
• 2,5-Dichloronitrobenzene
• 3,4-DICHLORONITROBENZENE,3,4-DICHLORONITROBENZENE PESTANAL,3,4-Dichloronitrobenzene, asym.-Nitro-o-dichlorobenzene
• Nitrobenzene
• 2,4-Dinitrotoluene
• 2,3-DICHLORONITROBENZENE PESTANAL, 250 M,2,3-DICHLORONITROBENZENE 99%,2,3-DICHLORONITROBENZENE
• 1,3-Dinitrobenzene