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ChemicalBook >  Product Catalog >  Organic Chemistry >  Carboxylic acids and derivatives >  (-)-Di-p-toluoyl-L-tartaric acid

(-)-Di-p-toluoyl-L-tartaric acid

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(-)-Di-p-toluoyl-L-tartaric acid Basic information

Product Name:
(-)-Di-p-toluoyl-L-tartaric acid
Synonyms:
  • (-)-Ditoluoyl-(L)-tartaric acid monohydrate
  • Di-4-Toluoyl-L-tartaric acid
  • (-)-2,3-DI-P-TOLUOYL-L-TARTARIC ACID
  • Di-p-Toluyl-L-Tartaric Acid Anhydrous
  • (-)-DI-O,O'-P-TOLUOYL-L-TARTARIC ACID
  • Di-Para-Toluoyl-D-TartaricAcid,Anhydrous
  • Di-Para-Toluoyl-L-TartaricAcid
  • Di-P-Toluoyl-L-TartaricAcid(Anhydrous)
CAS:
32634-66-5
MF:
C20H18O8
MW:
386.35
EINECS:
251-131-7
Product Categories:
  • chiral
  • Carboxylic Acids (Chiral)
  • Chiral Building Blocks
  • for Resolution of Bases
  • Optical Resolution
  • Synthetic Organic Chemistry
  • Pharmaceutical Intermediates
  • FINE Chemical & INTERMEDIATES
  • Chiral Compounds
  • Miscellaneous
  • CHIRAL CHEMICALS
  • Hydroxy Acids & Deriv.
  • Carboxylic AcidsAsymmetric Synthesis
  • Chiral Building Blocks
  • Chiral Compound
  • Inhibitors
  • Chiral Resolution Reagents
  • Chiral Resolving Reagents
  • Organic Building Blocks
Mol File:
32634-66-5.mol
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(-)-Di-p-toluoyl-L-tartaric acid Chemical Properties

Melting point:
169-171 °C(lit.)
alpha 
-142 º (c=10, EtOH)
Boiling point:
432.57°C (rough estimate)
Density 
1.3084 (rough estimate)
refractive index 
-139 ° (C=1, EtOH)
storage temp. 
Store below +30°C.
solubility 
Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka
1.46±0.25(Predicted)
form 
Crystalline Powder
color 
White to yellow
optical activity
[α]20/D 138°, c = 1 in ethanol
Water Solubility 
soluble
BRN 
2022481
CAS DataBase Reference
32634-66-5(CAS DataBase Reference)
EPA Substance Registry System
Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, [R-(R*,R*)]- (32634-66-5)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36/37-26
WGK Germany 
3
TSCA 
T
HS Code 
29181300

MSDS

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(-)-Di-p-toluoyl-L-tartaric acid Usage And Synthesis

Uses

(-)-di-p-toluoyl-l-tartaric acid can be used as a chiral resolving agent for the resolution of the racemic bases to isolate the (-)-enantiomeric forms.

Chemical Properties

white to light yellow crystal powde

Uses

Escitalopram intermediate

Uses

(-)-O,O’-Di-p-toluoyl-L-tartaric Acid is a useful reagent for the preparation of the upadacitinib salt compound.

Uses

Inhibitor of enzyme

General Description

(-)-O,O′-Di-p-toluoyl-L-tartaric acid is a O,O′-diacyl tartaric acid derivative that can be prepared by the resolution of its racemate in the presence of cinchonine.

(-)-Di-p-toluoyl-L-tartaric acidSupplier

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