(3R)-Vestitol
(3R)-Vestitol Basic information
- Product Name:
- (3R)-Vestitol
- Synonyms:
-
- (3R)-3β-(2-Hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol
- (3R)-Vestitol
- [R,(-)]-3,4-Dihydro-3-(2-hydroxy-4-methoxyphenyl)-2H-1-benzopyran-7-ol
- (3R)-Vestilol
- (3R)-3-(2-hydroxy-4-methoxy-phenyl)chroman-7-ol
- 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(2-hydroxy-4-methoxyphenyl)-, (3R)-
- (-)-vestitol
- CAS:
- 35878-41-2
- MF:
- C16H16O4
- MW:
- 272.3
- Mol File:
- 35878-41-2.mol
(3R)-Vestitol Chemical Properties
- Melting point:
- 154-156 °C
- Boiling point:
- 418.5±45.0 °C(Predicted)
- Density
- 1.282±0.06 g/cm3(Predicted)
- storage temp.
- -10 to -25°C
- solubility
- DMSO: 2mg/mL, clear
- pka
- 9.53±0.40(Predicted)
- form
- powder
- color
- white to beige
(3R)-Vestitol Usage And Synthesis
Uses
(R)-Vestitol is a Brazilian red propolis extract which may display antifungal activity.
Definition
ChEBI: A methoxyisoflavan that is (R)-isoflavan substituted by a methoxy group at position 4' and hydroxy groups at positions 7 and 2' respectively.
Biological Activity
Hydroxyisoflavan isolated from Cuban and Brazilian red propolis th at exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities.
Vestitol is a hydroxyisoflavan isolated from Cuban and Brazilian red propolis, licorice root and other sources th at exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities. Apparently Vestitol inhibits release of the chemokines CXCL1/KC and CXCL2/MIP-2 from macrophages. Vestitol strongly inhibits Chikungunya virus infection. Vestitol exhibits anti-trypanosomal activity against T. brucei and T. congolense (EC50 3.86 and 4.36 μg/ml.
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