D-alpha-Cyclohexylglycine Chemical Properties

Melting point:

256 °C

alpha 

-34.5 º (c=0.4 5N HCl)

Boiling point:

292.8±23.0 °C(Predicted)

Density 

1.120±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO

pka

2.44±0.10(Predicted)

form 

Solid

color 

Off-White

Water Solubility 

Soluble

BRN 

3196806

InChIKey

WAMWSIDTKSNDCU-SSDOTTSWSA-N

CAS DataBase Reference

14328-52-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

37/39-26-24/25

WGK Germany 

3

HS Code 

29224999

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

D-alpha-Cyclohexylglycine Usage And Synthesis

Description

D-alpha-Cyclohexylglycine is a kind of non-proteinogenic amino acid. It is widely presented in various natural products and pharmaceutical intermediates. It can be incorporated into the peptide inhibitors renders resistance from peptidases and proteinases and thereby imparts pharmacological stability to molecules. Some derivatives of Cyclohexylglycine has been recently been developed into inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes.

References

https://www.qmbio.com/?shopp_category=chg
Edmondson, Scott D., A. Mastracchio, and E. R. Parmee. "CYCLOHEXYLGLYCINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES." (2008).
Mastracchio, Anthony, et al. "Heterocycle-Fused Cyclohexylglycine Derivatives as Novel Dipeptidyl Peptidase-IV Inhibitors. " Cheminform 35.35(2004):203-206.

Chemical Properties

white powder

Uses

D-Cyclohexylglycine (cas# 14328-52-0) is a compound useful in organic synthesis.

D-alpha-Cyclohexylglycine(14328-52-0)Related Product Information

• Cyclohexanecarboxylic acid
• 4-Aminophenylacetic acid
• Isocyanatocyclohexane
• Citric acid
• Folic acid
• Diethylstilbestrol
• Molasses
• Nitrilotriacetic acid
• Iminodiacetic acid
• α-Lipoic Acid
• (Aminomethyl)cyclohexane
• Cyclohexylacetic acid
• Glycine
• Hyaluronic acid
• Sodium N-cyclohexylsulfamate
• Ethyl 2-(Chlorosulfonyl)acetate
• Ascoric Acid
• FMOC-D-ALPHA-CYCLOHEXYLGLYCINE,FMOC-CYCLOHEXYL-D-GLYCINE