Diethyl (2-oxopropyl)phosphonate Chemical Properties

Boiling point:

126 °C9 mm Hg(lit.)

Density 

1.01 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.433(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Miscible with tetrahydrofuran, ether, dichloromethane and chloroform.

form 

Liquid

color 

Clear colorless to light yellow

InChI

InChI=1S/C7H15O4P/c1-4-10-12(9,11-5-2)6-7(3)8/h4-6H2,1-3H3

InChIKey

RSAFKRSMGOSHRK-UHFFFAOYSA-N

SMILES

P(CC(=O)C)(=O)(OCC)OCC

CAS DataBase Reference

1067-71-6(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29319090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

Diethyl (2-oxopropyl)phosphonate Usage And Synthesis

Chemical Properties

CLEAR COLORLESS TO LIGHT YELLOW LIQUID

Uses

Diethyl (2-Oxopropyl)phosphonate, is used in the preparation of enantipure acetoxyalkanephosphonates thru dynamic enzymic kinetic resolution alpha- and beta-hydroxalkanephosphonates.

Synthesis Reference(s)

Tetrahedron, 34, p. 649, 1978 DOI: 10.1016/0040-4020(78)88099-5
Tetrahedron Letters, 17, p. 2829, 1976 DOI: 10.1016/S0040-4039(01)85513-1

reaction suitability

reaction type: C-C Bond Formation

Diethyl (2-oxopropyl)phosphonate(1067-71-6)Related Product Information

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• ACETYLPHOSPHONIC ACID DIETHYL ESTER
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• Celiprolol