ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Basic information
- Product Name:
- 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione
- Synonyms:
-
- 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione
- N-(3-Chloro-2-hydroxypropyl)phthalimide
- Rivaroxaban Impurity 120
- 1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)-
- 2-(3-Chloro-2-hydroxypropyl)isoindoline-1,3-dione
- CAS:
- 19667-37-9
- MF:
- C11H10ClNO3
- MW:
- 239.65
- Mol File:
- 19667-37-9.mol
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2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Chemical Properties
- Melting point:
- 95-96.5 °C
- Boiling point:
- 405.4±35.0 °C(Predicted)
- Density
- 1.444±0.06 g/cm3(Predicted)
- pka
- 13.25±0.20(Predicted)
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2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Usage And Synthesis
Uses
2-(3-Chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione has been used in yeast biosynthesis of (S)-adrenergic β-blockers by stereoselective reduction of haloketones. It has also been used in a validated LC-?MS?/MS method for the determination of three genotoxic impurities in rivaroxaban drug substance.
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