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ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Standard Substance >  11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

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11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Basic information

Product Name:
11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
Synonyms:
  • 21-deoxycortisol
  • 21 DEOXYCORTISOL 21-DESOXYCORTISOL
  • 21-DESOXYCORTISOL
  • 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
  • 11BETA,17ALPHA-DIHYDROXY-PROGESTERONE
  • 4-PREGNENE-11BETA,17ALPHA-DIOL-3,20-DIONE
  • 4-PREGNEN-11BETA,17ALPHA-DIOL-3,20-DIONE
  • 4-PREGNEN-11-BETA, 17-DIOL-3,20-DIONE
CAS:
641-77-0
MF:
C21H30O4
MW:
346.46
EINECS:
211-375-7
Product Categories:
  • Steroids
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
641-77-0.mol
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11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Chemical Properties

Melting point:
225-228 °C
Boiling point:
523.9±50.0 °C(Predicted)
Density 
1.21±0.1 g/cm3(Predicted)
Flash point:
9℃
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
12.86±0.70(Predicted)
color 
White to Pale Yellow
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Safety Information

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
7-16-36/37-45
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
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11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

21-Deoxy Cortisol (Hydrocortisone EP Impurity L) is a metabolite of Fluticasone propionate (F599500).

Uses

A metabolite of Fluticasone propionate (F599500).

Definition

ChEBI: 21-deoxycortisol is a deoxycortisol that is 17xi-pregn-4-ene-3,20-dione substituted by a beta-hydroxy group at position 11 and an alpha-hydroxy group at position 17. It is a marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency. It has a role as a human blood serum metabolite and a mouse metabolite. It is an 11beta-hydroxy steroid, a 17alpha-hydroxy-C21-steroid, a tertiary alpha-hydroxy ketone and a deoxycortisol.

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