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Rufloxacin hydrochloride

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Rufloxacin hydrochloride Basic information

Product Name:
Rufloxacin hydrochloride
Synonyms:
  • RUFLOXACIN HCL
  • RUFLOXACIN HYDROCHLORIDE
  • 7h-pyrido(1,2,3-de)(1,4)benzothiazine-6-carboxylicacid,2,3-dihydro-9-fluoro-1
  • mf-934
  • RUFLOXACINHYDROCHLORIDE(SUBJECTTOPATENTFREE)
  • 2,3-Dihydro-9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acid hydrochloride
  • 3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1
  • 4-benzothiazine-6-carboxylic acid
CAS:
106017-08-7
MF:
C17H19ClFN3O3S
MW:
399.87
Mol File:
106017-08-7.mol
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Rufloxacin hydrochloride Chemical Properties

Melting point:
322-324℃
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly, Heated), Water (Very Slightly)
form 
Off-white to light green crystalline solid.
color 
Off-White to Pale Yellow
CAS DataBase Reference
106017-08-7(CAS DataBase Reference)
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Safety Information

Toxicity
LD50 in rats, mice (mg/kg): 285, 224 i.v.; LD50 in rabbits, male, female rats (mg/kg): 660, 631, 501 orally (Cecchetti)
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Rufloxacin hydrochloride Usage And Synthesis

Description

Rufloxacin hydrochloride is another fluoroquinolone orally active antibacterial structurally and mechanistically related to temafloxacin and tosufloxacin. It is useful for the treatment of respiratory and urinary tract infections and also chronic bacterial prostatitis. Good tissue penetration with long acting activity has been reported.

Originator

Mediolanum (Italy)

Uses

Rufloxacin Hydrochloride inhibits human organic cation transporter 1 (hoCT1) (SLC22A1) but not hOCT2 (SLC22A2), and hOCT3 (SLC22A3) expressed in human embryonic kidney cell.

brand name

Qari; Monos

Rufloxacin hydrochloride Preparation Products And Raw materials

Preparation Products

RUFLOXACIN

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