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5-Methoxyindole-3-acetic acid

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5-Methoxyindole-3-acetic acid Basic information

Product Name:
5-Methoxyindole-3-acetic acid
Synonyms:
  • 2-(5-Methoxy-3-indolyl)acetic acid
  • 5-Methoxy-3-indoleacetic acid 98%
  • 5-methoxy-indole-3-aceticaci
  • 5-methoxyindoleaceticacid
  • RARECHEM AL BO 1466
  • TIMTEC-BB SBB003497
  • 5-METHOXYINDOLE-3-ACETIC ACID
  • 5-METHOXY-3-INDOLEACETIC ACID
CAS:
3471-31-6
MF:
C11H11NO3
MW:
205.21
EINECS:
222-438-3
Product Categories:
  • Indoline & Oxindole
  • Indoles and derivatives
  • Heterocyclic Compounds
  • Indoles
  • Simple Indoles
  • Building Blocks
  • Heterocyclic Building Blocks
Mol File:
3471-31-6.mol
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5-Methoxyindole-3-acetic acid Chemical Properties

Melting point:
145-148 °C (dec.)(lit.)
Boiling point:
343.88°C (rough estimate)
Density 
1.2235 (rough estimate)
refractive index 
1.5130 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
crystalline
pka
4.52±0.30(Predicted)
color 
light yellow to tan
Water Solubility 
insoluble
BRN 
187161
CAS DataBase Reference
3471-31-6(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
RTECS 
NL3660500
HS Code 
29339900

MSDS

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5-Methoxyindole-3-acetic acid Usage And Synthesis

Chemical Properties

OFF-WHITE TO SLIGHTLY BEIGE CRYSTALLINE POWDER

Uses

Reactant for preparation of aryloxybenzothiazoles as inhibitors of NO production 1 Reactant for preparation of transcription inhibitors of novel Gli1 as antitumor agents Reactant for preparation of indole derivatives as NR2B/NMDA receptor antagonists 2 Reactant for preparation of indolyl esters and amides related to indomethacin as selective COX-2 inhibitors 3 Reactant for preparation of quinoline salicylic acid series of P-selectin antagonists 4 Reactant for preparation of prostaglandin D2 receptor antagonists.

Uses

5-Methoxyindole-3-acetic Acid is a chemical reagent used in the analysis of the physiological properties of auxins.

Uses

  • Reactant for preparation of aryloxybenzothiazoles as inhibitors of NO production
  • Reactant for preparation of transcription inhibitors of novel Gli1 as antitumor agents
  • Reactant for preparation of indole derivatives as NR2B/NMDA receptor antagonists
  • Reactant for preparation of indolyl esters and amides related to indomethacin as selective COX-2 inhibitors
  • Reactant for preparation of quinoline salicylic acid series of P-selectin antagonists
  • Reactant for preparation of prostaglandin D2 receptor antagonists

Definition

ChEBI: 5-methoxyindole-3-acetic acid is a member of the class of indole-3-acetic acids in which the hydrogen at position 5 of indole-3-acetic acid has been replaced by a methoxy group. It has a role as a Brassica napus metabolite, a human urinary metabolite, an antibacterial agent, a marine xenobiotic metabolite, a carcinogenic agent and a rat metabolite. It is a member of indole-3-acetic acids and an aromatic ether.

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