DIETHYL 2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE Chemical Properties

Melting point:

72-74 °C (lit.)

Boiling point:

208 °C/40 mmHg (lit.)

Density 

1.1667 (rough estimate)

refractive index 

1.4800 (estimate)

storage temp. 

Sealed in dry,Room Temperature

form 

powder to crystal

pka

2.81±0.20(Predicted)

color 

White to Orange to Green

InChI

1S/C13H17NO4/c1-5-17-12(15)10-7-11(13(16)18-6-2)9(4)14-8(10)3/h7H,5-6H2,1-4H3

InChIKey

DIIWSYPKAJVXBV-UHFFFAOYSA-N

SMILES

CCOC(=O)c1cc(C(=O)OCC)c(C)nc1C

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2933.39.9200

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

MSDS

• Language:English Provider:SigmaAldrich

DIETHYL 2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE Usage And Synthesis

Uses

Diethyl 2,6-dimethylpyridine-3,5-dicarboxylate is formed during the oxidation of 4-substituted Hantsch dihydropyridines in presence of methanesulfonic acid, sodium nitrite and wet SiO₂ as oxidizing agents.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 2, p. 214, 1943
Tetrahedron, 28, p. 5911, 1972
Tetrahedron Letters, 34, p. 623, 1993 DOI: 10.1016/S0040-4039(00)61635-0

General Description

Diethyl 2,6-dimethylpyridine-3,5-dicarboxylate is formed during the oxidation of 4-substituted Hantsch dihydropyridines in presence of methanesulfonic acid, sodium nitrite and wet SiO₂ as oxidizing agents.

DIETHYL 2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE(1149-24-2)Related Product Information

• diethyl 3,6-dimethyl-2,5-pyridinedicarboxylate
• DIETHYL 2-METHYL-6-(TRIFLUOROMETHYL)PYRIDINE-3,5-DICARBOXYLATE
• DIETHYL 4-(4-METHOXYPHENYL)-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE
• DIETHYL 2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE
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