7-Hydroxygranisetron
7-Hydroxygranisetron Basic information
- Product Name:
- 7-Hydroxygranisetron
- Synonyms:
-
- 1H-INDAZOL-3-CARBONIC ACID
- 1H-INDAZOLE-3-CARBOXYLIC ACID
- 1H-INDAZOLE-3-CARBONIC ACID
- AKOS BB-9978
- 3-INDAZOLECARBOXYLIC ACID
- 3-CARBOXYINDAZOLE
- ndazole-3-carboxylic acid
- INDAZOLE-3-CARBOXYLIC ACID
- CAS:
- 4498-67-3
- MF:
- C8H6N2O2
- MW:
- 162.15
- EINECS:
- 224-794-5
- Product Categories:
-
- Indoles and derivatives
- pharmacetical
- Acids and Derivatives
- Heterocycles
- Carboxylic Acids
- Organic acids
- PHARMACEUTICAL INTERMEDIATES
- (intermediate of granisetron)
- Indazoles
- Indole Derivatives
- Carboxylic Acids
- Fused Ring Systems
- Building Blocks
- Heterocyclic Building Blocks
- Mol File:
- 4498-67-3.mol
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7-Hydroxygranisetron Chemical Properties
- Melting point:
- 266-270 °C (dec.)
- Boiling point:
- 443.7±18.0 °C(Predicted)
- Density
- 1.506±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 3.03±0.10(Predicted)
- form
- powder
- color
- beige
- BRN
- 6354
- InChI
- InChI=1S/C8H6N2O2/c11-8(12)7-5-3-1-2-4-6(5)9-10-7/h1-4H,(H,9,10)(H,11,12)
- InChIKey
- BHXVYTQDWMQVBI-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC=C2)C(C(O)=O)=N1
- CAS DataBase Reference
- 4498-67-3(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36-36/37/38
- Safety Statements
- 26-36/37/39-22
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29339900
MSDS
- Language:English Provider:SigmaAldrich
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7-Hydroxygranisetron Usage And Synthesis
Chemical Properties
yellow crystal
Uses
Indazole-3-carboxylic acid may be used in the synthesis of the following:
- N-(8-methyl-azabicyclo[3.2.11]oct-3-yl)-1H-indazole-3-carboxamide
- N-(1- benzyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-1H-indazole-3-carboxamide
- 1H-indazole-3-carboxamide
Uses
Indazole-3-carboxylic acid is indole derivatives useful in treatment of pain and inflammation
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 26, p. 531, 1989 DOI: 10.1002/jhet.5570260251
7-Hydroxygranisetron Preparation Products And Raw materials
Raw materials
Sodium hydroxideHydrochloric acidSulfuric acid Acetic acid glacialSodium nitriteStannous chloride dihydrateSTANNOUS CHLORIDEIsatin
Preparation Products
7-HydroxygranisetronSupplier
Xishi Chemical (Shanghai) Co., Ltd. Gold
- Tel
- 021-60499358 13661956116
- info@cs-pharm.com
Suzhou Actchem Co,. Ltd, Gold
- Tel
- +86-18762124502
- actchem@qq.com
Baiyin Longsheng Chemical CO;Ltd Gold
- Tel
- 0943-8396606 18194331635
- 232619671@qq.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 021-61259108 18621169109
- market03@meryer.com
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7-Hydroxygranisetron(4498-67-3)Related Product Information
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- 1H-INDAZOLE-5-BORONIC ACID
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- Indometacin
- INDOMETHACIN SODIUM
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- 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE
- 6-Hydroxyindole
- Indole-4-carboxylic acid
- Ascoric Acid