2-Chloro-5-trichloromethylpyridine Chemical Properties

Melting point:

-18.14 °C

Boiling point:

281.8±35.0 °C(Predicted)

Density 

1.582±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

solid

pka

-2.26±0.10(Predicted)

color 

Pink

CAS DataBase Reference

69045-78-9(CAS DataBase Reference)

EPA Substance Registry System

2-Chloro-5-(trichloromethyl)pyridine (69045-78-9)

Safety Information

Hazard Codes 

Xi,T

Risk Statements 

36/37/38-25

Safety Statements 

26-37/39-45

RIDADR 

UN2811

Hazard Note 

Irritant

HS Code 

2933399990

2-Chloro-5-trichloromethylpyridine Usage And Synthesis

Synthesis

A synthetic method of 2-chloro-5-trichloromethyl pyridine comprises the following steps of (1) synthesis of N-oxygen-3-methylpyridine: reacting by taking 3-methylpyridine as a raw material, glacial acetic acid as a solvent and 60% hydrogen peroxide as an oxidizing agent to obtain N-oxygen-3-methylpyridine; (2) synthesis of 2-chloro-5-methylpyridine: carrying out oriented chlorination on N-oxygen-3-methylpyridine by taking benzoyl chloride as a chlorinating agent to obtain 2-chloro-5-methylpyridine; (3) synthesis of 2-chloro-5-trichloromethyl pyridine: reacting by taking methyl ethyl ketone peroxide as an initiating agent to obtain a crude 2-chloro-5-trichloromethyl pyridine product; (4) refining of 2-chloro-5-trifluoromethyl pyridine: carrying out halogen exchange fluoridation reaction by taking excessive potassium fluoride as a fluorizating agent, dimethyl sulfoxide as a solvent and hexadecyl trimethyl ammonium bromide as a phase transfer catalyst, and rectifying and purifying to obtain a fine 2-chloro-5-trichloromethyl pyridine product.

2-Chloro-5-trichloromethylpyridine(69045-78-9)Related Product Information

• 2-Chloro-3-(trifluoromethyl)pyridine
• Nitrapyrin
• 2,3,4,5-Tetrachloro-6-(trichloromethyl)pyridine
• 2-Chloro-5-trichloromethylpyridine
• 2-CHLORO-5-(CHLOROMETHYL)PYRIDINE HYDROCHLORIDE
• 3-Picolyl chloride hydrochloride
• 2,6-dichloro-3-(trichloromethyl)pyridine
• 2-Chloro-5-chloromethylpyridine
• 3-(CHLOROMETHYL)PYRIDINE
• 2,3-Dichloro-5-(trichloromethyl)pyridine