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2-Chloro-5-trichloromethylpyridine

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2-Chloro-5-trichloromethylpyridine Basic information

Product Name:
2-Chloro-5-trichloromethylpyridine
Synonyms:
  • IFLAB-BB F0797-0001
  • 2-CHLORO-5-TRICHLOROMETHYL PYRIDINE
  • AKOS BBS-00000412
  • 2-Chloro-5-trichloromethylpyridine###NA
  • Pyridine, 2-chloro-5-(trichloromethyl)-
  • oro-5-trichL
  • 2-Chloro-5-trichloromethylpyridine ISO 9001:2015 REACH
CAS:
69045-78-9
MF:
C6H3Cl4N
MW:
230.91
EINECS:
614-911-1
Product Categories:
  • Halides
  • Pyridines
  • Pyridine
  • API Intermediate
  • Heterocycle-Pyridine series
  • Imidazoles
Mol File:
69045-78-9.mol
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2-Chloro-5-trichloromethylpyridine Chemical Properties

Melting point:
-18.14 °C
Boiling point:
281.8±35.0 °C(Predicted)
Density 
1.582±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-2.26±0.10(Predicted)
form 
solid
color 
Pink
CAS DataBase Reference
69045-78-9(CAS DataBase Reference)
EPA Substance Registry System
2-Chloro-5-(trichloromethyl)pyridine (69045-78-9)
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Safety Information

Hazard Codes 
Xi,T
Risk Statements 
36/37/38-25
Safety Statements 
26-37/39-45
RIDADR 
UN2811
Hazard Note 
Irritant
HS Code 
2933399990
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2-Chloro-5-trichloromethylpyridine Usage And Synthesis

Synthesis

A synthetic method of 2-chloro-5-trichloromethyl pyridine comprises the following steps of (1) synthesis of N-oxygen-3-methylpyridine: reacting by taking 3-methylpyridine as a raw material, glacial acetic acid as a solvent and 60% hydrogen peroxide as an oxidizing agent to obtain N-oxygen-3-methylpyridine; (2) synthesis of 2-chloro-5-methylpyridine: carrying out oriented chlorination on N-oxygen-3-methylpyridine by taking benzoyl chloride as a chlorinating agent to obtain 2-chloro-5-methylpyridine; (3) synthesis of 2-chloro-5-trichloromethyl pyridine: reacting by taking methyl ethyl ketone peroxide as an initiating agent to obtain a crude 2-chloro-5-trichloromethyl pyridine product; (4) refining of 2-chloro-5-trifluoromethyl pyridine: carrying out halogen exchange fluoridation reaction by taking excessive potassium fluoride as a fluorizating agent, dimethyl sulfoxide as a solvent and hexadecyl trimethyl ammonium bromide as a phase transfer catalyst, and rectifying and purifying to obtain a fine 2-chloro-5-trichloromethyl pyridine product.

2-Chloro-5-trichloromethylpyridine Preparation Products And Raw materials

Preparation Products

2-Chloro-5-trichloromethylpyridineSupplier

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