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2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

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2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Basic information

Product Name:
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
Synonyms:
  • 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
  • Eltrombopag Impurity 35
  • 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one
  • 2-(3,4-dimethylphenyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one
  • Eltrombopag Intermediate 1
  • EltroMbopag II
  • 2-Oxo-2,4,5,6,7,7a-Hexahydrothieno [3,2-c] Pyridine
  • 1-(3,4-diMethylphenyl)-3-Methyl-1H-pyrazol-5-ol
CAS:
277299-70-4
MF:
C12H14N2O
MW:
202.25
EINECS:
1592732-453-0
Mol File:
277299-70-4.mol
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2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Chemical Properties

Melting point:
121.0 to 125.0 °C
Boiling point:
338.5±52.0 °C(Predicted)
Density 
1.121
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
0.79±0.40(Predicted)
color 
Pale Beige to Light Beige
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Safety Information

HS Code 
2933.19.9000
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2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Usage And Synthesis

Uses

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one, is an impurity of Eltrombopag (E508000), which is agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-oneSupplier

Shenzhen HwaGen Pharmaceutical Co.,Ltd Gold
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Jinan XuanDe Chemical Co., Ltd. Gold
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0531-88803958; 18866891188
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ShenZhen H&D Pharmaceutical Technology Co., LTD Gold
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13986652530
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zhangweiyue@hdimpurity.com
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2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one(277299-70-4)Related Product Information