Basic information Safety Supplier Related

Sancycline hydrochloride

Basic information Safety Supplier Related

Sancycline hydrochloride Basic information

Product Name:
Sancycline hydrochloride
Synonyms:
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4A,5,5A,6,11,12A-octahydro-3,10,12,12A-tetrahydroxy-1,11-dioxo-, monohydrochloride, [4S-(4.alpha.,4A.alpha.,5A.alpha.,12A.alpha.)]-
  • 2-Naphthacenecarboxamide, 4-dimethylamino-1,4,4A,5,5A,6,11,12A-octahydro-3,10,12,12A-tetrahydroxy-1,11-dioxo-, hydrochloride
  • Bonomycin hydrochloride
  • Fda 0129
  • (4S,4aS,5aR,12aS)-4-(DiMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1-11-dioxo-2-naphthacenecarboxaMide Hydrochloride
  • 6-DeMethyl-6-deoxytetracycline Hydrochloride
  • Minocycline EP IMpurity B
  • 6-DeMethyl-6-deoxytetracycline hydrochloride, NSC 51812
CAS:
6625-20-3
MF:
C21H23ClN2O7
MW:
450.86952
Product Categories:
  • Amines
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
6625-20-3.mol
More
Less

Sancycline hydrochloride Chemical Properties

Melting point:
224-2280C (dec.)
storage temp. 
-20°C Freezer
solubility 
DMF: 20mg/mL; DMSO: 20mg/mL; DMSO:PBS (pH 7.2) (1:5): 0.15 mg/mL; Ethanol: 5mg/mL
form 
A crystalline solid
More
Less

Sancycline hydrochloride Usage And Synthesis

Chemical Properties

Yellow Solid

Uses

Sancycline Hydrochloride (Minocycline EP Impurity B) is a semi-synthetic antibiotic related to Tetracycline.

Uses

Sancycline hydrochloride is the hydrochloride salt of a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin, first reported in 1962. As the simplest of the early tetracyclines, sancycline was the first to be totally synthesised by Conover and co-workers. Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.

Sancycline hydrochlorideSupplier

Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd Gold
Tel
18502726233
Email
3641133981@qq.com
Hubei wei shi reagent group ltd., company Gold
Tel
027-59101766 13125137661
Email
2853877621@qq.com
Shanghai Boyle Chemical Co., Ltd.
Tel
Email
sales@boylechem.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com