2,8-Quinolinediol Chemical Properties

Melting point:

~290 °C (dec.)

Boiling point:

403.2±45.0 °C(Predicted)

Density 

1.337±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly, Heated)

form 

Solid

pka

8.85±0.20(Predicted)

color 

Dark Reddish Brown

λmax

335nm(EtOH)(lit.)

BRN 

472906

CAS DataBase Reference

15450-76-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-36/38

Safety Statements 

26-36-37/39

WGK Germany 

3

HS Code 

2933499090

MSDS

• Language:English Provider:SigmaAldrich

2,8-Quinolinediol Usage And Synthesis

Chemical Properties

Brown Powder

Uses

2,8-Quinolinediol is suitable for use as standard in a study to identify the urinary metabolites for the toxicity related processes and pathogenesis induced by doxorubicin (DOX) to rats by online and off-line LC-MS techniques. It may be used as starting reagent for the preparation of two powerful β2-adrenergic receptor agonists, used for the treatment of asthma:

• Procaterol
• Indacaterol

Uses

2,8-Quinolinediol is a substituted quinolinone derivative used in the preparation of pharmaceutical compounds.

Definition

ChEBI: Quinoline-2,8-diol is a dihydroxyquinoline. It is a tautomer of an 8-hydroxyquinolin-2(1H)-one.

General Description

2,8-Quinolinediol is a quinolone derivative. It has been reported as metabolite of 8-hydroxyquinoline-N-oxide in rabbits. Synthesis of 2,8-quinolinediol has been reported. It is reported as one of the six possible forms of 8-hydroxycarbostyril. It has been detected as new UV-absorbing compound (UAC) in cow milk and its structure was elucidated using HRMS and by ¹H, ¹³C and ¹H ×¹³C NMR.It is also known as 8-hydroxycarbostyril or 8-hydroxyquinolin-2(1H)-one.

2,8-Quinolinediol(15450-76-7)Related Product Information

• 8-Hydroxyquinoline
• Quinhydrone
• Propylene glycol
• 6-Hydroxyquinoline
• 1,2-Hexanediol
• Quinolinic acid
• Isoquinoline
• Quinclorac
• 2-Quinolinol
• Ethoxyquin
• 4-Hydroxyquinoline
• 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline
• 5-ForMyl-8-hydroxycarbostyril
• 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
• 5-ACETYL-8-HYDROXY-1H-QUINOLIN-2-ONE
• Indacaterol Impurity 12
• (S)-Indacaterol
• 2(1H)-Quinolinone, 5,5'-[[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)imino]bis(1-hydroxy-2,1-ethanediyl)]bis[8-(phenylmethoxy)-