Coronarin D methyl ether
Coronarin D methyl ether Basic information
- Product Name:
- Coronarin D methyl ether
- Synonyms:
-
- Coronarin D methyl ether
- 2(3H)-Furanone,3-[[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methylene]dihydro-5-methoxy-,(3E)-
- CAS:
- 157528-81-9
- MF:
- C21H32O3
- MW:
- 332.48
- Mol File:
- 157528-81-9.mol
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Coronarin D methyl ether Chemical Properties
- Boiling point:
- 447.8±45.0 °C(Predicted)
- Density
- 1.04±0.1 g/cm3(Predicted)
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Coronarin D methyl ether Usage And Synthesis
Uses
Methoxycoronarin D can be isolated from Hedychium coronarium J. Koenig and is a potent inhibitor of NF-κB with an IC50 value of 7.3 μM. Methoxycoronarin D is also a selective inhibitor of COX-1 with an IC50 value of 0.9 μM[1].
References
[1] Endringer D C, et al. Cancer chemoprevention activity of labdane diterpenes from rhizomes of Hedychium coronarium[J]. Revista Brasileira de Farmacognosia, 2014, 24: 408-412.
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