Ervamycine Chemical Properties

Boiling point:

514.6±50.0 °C(Predicted)

Density 

1.27±0.1 g/cm3(Predicted)

pka

7.66±0.60(Predicted)

Ervamycine Usage And Synthesis

Description

This alkaloid from Vinca herbacea has been isolated as the crystalline hydrochloride, m.p. 184-6°C (dec.). The free base has [α]²³_D - 310° ± 2° (c 0.32, CHC13). Hydrogenation over Pt02 gives the 6:7-dihydro derivative which has [α]²⁶_D - 412.8° (c 0.606, CHCI3). When heated at 100°C with 5N-HC1, the latter is simultaneously hydrolyzed and decarboxylated to furnish 16-methoxy- 1: 2-dehydro-( - )-aspidospermidine.

Definition

ChEBI: 16-methoxytabersonine is the 16-methoxy derivative of tabersonine. It is a monoterpenoid indole alkaloid, an organic heteropentacyclic compound, a methyl ester and a tertiary amino compound. It is functionally related to a tabersonine. It is a conjugate base of a 16-methoxytabersoninium(1+).

References

Pyuskyulev et al., Collect. Czech. Chem. Commun., 32, 1289 (1967)

Ervamycine(27773-39-3)Related Product Information

• 17,18-Dehydroapovinvamine
• (3alpha,14beta,16alpha)-14,15-dihydro-14-hydroxyeburnamenine-14-carboxylic acid
• alpha-Cyperone
• beta-Sitosterol
• (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
• MOSLOFLAVONE
• Artemether
• beta-Eudesmol
• alpha-Terpineol
• hydroxygenkwanin
• Hydroxyecdysone
• 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
• 11-Hydroxytabersonine
• 17,18-Didehydrovincamine
• Vincamine Impurity
• 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid, 13a-ethyl-2,3,5,6,13a,13b-hexahydro-8-methoxy-, methyl ester, (13aS,13bS)-
• Eburnamenine-14-carboxylic acid, 14,15-dihydro-10,14-dihydroxy-, methyl ester, (3α,14β,16α)- (9CI)
• Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-15-hydroxy-, methyl ester, (5α,12R,19α)-