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Isogosferol

Basic information Safety Supplier Related

Isogosferol Basic information

Product Name:
Isogosferol
Synonyms:
  • Isogosferol
  • Isogospherol
  • 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2R)-2-hydroxy-3-methyl-3-buten-1-yl]oxy]-
  • 9-(2-hydroxy-3-methylbut-3-enoxy)furo[3,2-g]chromen-7-one
CAS:
53319-52-1
MF:
C16H14O5
MW:
286.28
Mol File:
53319-52-1.mol
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Isogosferol Chemical Properties

solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
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Isogosferol Usage And Synthesis

Description

Isogosferol is a minor furocoumarin of Murraya koenigii seeds.

Uses

Isogosferol ((+)-Isogospherol; Isogospherol) is a potent anti-inflammatory agent. Isogosferol decreases LPS (HY-D1056)-stimulated NO and IL-1β expression. Isogosferol decreases the LPS (HY-D1056)-stimulated expression of iNOS, COX-2, NF-κB, and pERK1/2[1].

References

[1] Song HY, et al. Anti-Inflammatory Activities of Isogosferol, a Furanocoumarin Isolated from Citrus junos Seed Shells through Bioactivity-Guided Fractionation. Molecules. 2019 Nov 12;24(22):4088. DOI:10.3390/molecules24224088

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