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Isothymusin

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Isothymusin Basic information

Product Name:
Isothymusin
Synonyms:
  • 6,7-dimethoxy-5,8,4′-trihydroxyflavone
  • Isothymusin
  • 5,8-Dihydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one
  • 4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-
CAS:
98755-25-0
MF:
C17H14O7
MW:
330.29
Mol File:
98755-25-0.mol
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Isothymusin Chemical Properties

Melting point:
214-215 °C(Solv: ethyl acetate (141-78-6); methanol (67-56-1))
Boiling point:
628.9±55.0 °C(Predicted)
Density 
1.483±0.06 g/cm3(Predicted)
pka
7.08±0.40(Predicted)
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Isothymusin Usage And Synthesis

Uses

Isothymusin is a potent anti-oxidant agent. Isothymusin shows radical scavenging activities. Isothymusin shows anti-proliferative activities in cancer cell lines. Isothymusin inhibited the enzymes associated with the promotion stage of cancer, including cycloxygenase- 2 and lipoxygenase-5[1][2].

References

[1] Kelm MA, et al. Antioxidant and cyclooxygenase inhibitory phenolic compounds from Ocimum sanctum Linn. Phytomedicine. 2000 Mar;7(1):7-13. DOI:10.1016/S0944-7113(00)80015-X
[2] Singh S, et al. Isothymusin, a Potential Inhibitor of Cancer Cell Proliferation: An In Silico and In Vitro Investigation. Curr Top Med Chem. 2020;20(21):1898-1909. DOI:10.2174/1568026620666200710103636

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