N-Demethylechitamine
N-Demethylechitamine Basic information
- Product Name:
- N-Demethylechitamine
- Synonyms:
-
- N-Demethylechitamine
- 13H-3,8a-Methano-1H-azepino[1',2':1,2]pyrrolo[2,3-b]indole-14-carboxylic acid, 4-ethylidene-2,3,4,5,7,8-hexahydro-1-hydroxy-14-(hydroxymethyl)-, methyl ester, (1S,3S,4E,6S,8aS,13aR,14R)-
- Nb-demethylechitamine
- CAS:
- 60048-88-6
- MF:
- C21H26N2O4
- MW:
- 370.44
- Mol File:
- 60048-88-6.mol
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N-Demethylechitamine Chemical Properties
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
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N-Demethylechitamine Usage And Synthesis
Uses
Nb-Demethylechitamine is an alkaloid isolated from the methanol extract of Alstonia rostrata twigs. Nb-Demethylechitamine has in vitro cytotoxic activity against several human cancer cell lines, including human myeloid leukemia HL-60, liver cancer SMMC-7721, lung cancer A-549, breast cancer MCF-7, and colon cancer SW480 cells[1].
References
[1] Yuan YX, et al. Two new monoterpenoid indole alkaloids from Alstonia rostrata. Nat Prod Res. 2018 Apr;32(7):844-848. DOI:10.1080/14786419.2017.1360886
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