5-Methylpyridine-2,3-dicarboxylic acid dimethyl ester Chemical Properties

Melting point:

45-50°C

Boiling point:

292.2±35.0 °C(Predicted)

Density 

1.197

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform, DMSO (Slightly), Methanol (Slightly)

pka

-0.54±0.10(Predicted)

form 

Solid

color 

Off-White

InChI

InChI=1S/C10H11NO4/c1-6-4-7(9(12)14-2)8(11-5-6)10(13)15-3/h4-5H,1-3H3

InChIKey

MKOJTLPEGLTEFM-UHFFFAOYSA-N

SMILES

C1(C(OC)=O)=NC=C(C)C=C1C(OC)=O

EPA Substance Registry System

2,3-Pyridinedicarboxylic acid, 5-methyl-, 2,3-dimethyl ester (112110-16-4)

5-Methylpyridine-2,3-dicarboxylic acid dimethyl ester Usage And Synthesis

Chemical Properties

White or of- white powder or crystlline power,odorless.

Uses

5-methylpyridine-2,3-dicarboxylic acid dimethyl ester (MPE) could used as the raw material to synthesize 5-bromomethylpyridine-2,3-dicarboxylic acid methyl ester via a bromination reaction with N-bromosuccinimide (NBS) as the brominating reagent and azobisisobutyronitrile (AIBN) as an initiator[1].

References

[1] Ma X, et al. Mechanism and Kinetics of Bromination of 5-Methylpyridine-2,3-dicarboxylic Acid Dimethyl Ester. Russian Journal of Physical Chemistry A, 2023; 97: 73–79.

5-Methylpyridine-2,3-dicarboxylic acid dimethyl ester(112110-16-4)Related Product Information

• Biphenyl dimethyl dicarboxylate