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Gypenoside XLIX

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Gypenoside XLIX Basic information

Product Name:
Gypenoside XLIX
Synonyms:
  • (3S,5S,8R,9S,10S,13R,14R,17S)-17-[(2S)-2-hydroxy-6-methyl-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-3-[(2S,3R,4S,5S)-5-hydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-4,4,8,14-tetramethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
  • Gypenoside XLIX
  • (3beta)-3-[(O-6-Deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-xylopyranosyl-(1-3)]-alpha-L-arabinopyranosyl)oxy]-21-(beta-D-glucopyranosyloxy)-20-hydroxy-dammar-24-en-19-al
  • Dammar-24-en-19-al, 3-[(O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-α-L-arabinopyranosyl)oxy]-21-(β-D-glucopyranosyloxy)-20-hydroxy-, (3β)-
  • (3β)-3-{[6-Deoxy-α-L-mannopyranosyl-(1-2)-[β-D-xylopyranosyl-(1-3)]-α-L-arabinopyranosyl]oxy}-20-hydroxy-19-oxodammar-24-en-21-ylβ-D-glucopyranoside
  • Gynostemma Extract – Gypenoside
  • Gypenoside A (xlix)
  • Gypenoside XLIX-RM
CAS:
94987-08-3
MF:
C52H86O21
MW:
1047.23
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Inhibitors
Mol File:
94987-08-3.mol
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Gypenoside XLIX Chemical Properties

Boiling point:
1105.1±65.0 °C(Predicted)
Density 
1.41
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO : 125 mg/mL (119.36 mM; Need ultrasonic)
form 
powder
pka
12.95±0.70(Predicted)
color 
White
InChIKey
AFEVCSJFNQWWDF-AZFNEDKCSA-N
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Gypenoside XLIX Usage And Synthesis

Chemical Properties

White crystal, soluble in methanol, ethanol, DMSO and other organic solvents, from gynostemma (gynostemma saponins and ginsenosides physiological activity is similar. (Gynostemma saponins and ginsenosides are similar in physiological activity. Therefore, gynostemma has the reputation of "southern ginseng" and "the second ginseng").

Uses

Gypenoside XLIX is a naturally occurring gynosaponin inhibits NF-κB activation via a PPAR-α-dependent pathway.

IC 50

PPAR-α

Gypenoside XLIXSupplier

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