Vilazodone-d8
Vilazodone-d8 Basic information
- Product Name:
- Vilazodone-d8
- Synonyms:
-
- 5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-(piperazinyl-d8)]-2-benzofurancarboxaMide
- EMD 515259-d8
- Vilazodone-d8
- Vilazodone D8Q: What is Vilazodone D8 Q: What is the CAS Number of Vilazodone D8 Q: What is the storage condition of Vilazodone D8 Q: What are the applications of Vilazodone D8
- 5-{4-[4-(5-cyano-1H-indol-3-yl)butyl](2,2,3,3,5,5,6,6-2H?)piperazin-1-yl}-1-benzofuran-2-carboxamide
- CAS:
- 1794789-93-7
- MF:
- C26H26N5O2
- MW:
- 440.51694
- Product Categories:
-
- Amines
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Isotope Labelled Compounds
- Pharmaceuticals
- Mol File:
- 1794789-93-7.mol
Vilazodone-d8 Chemical Properties
- Melting point:
- 195-198°C
- storage temp.
- Refrigerator
- solubility
- Water: 0.32 mg/ml
- form
- A solid
- color
- White to off-white
Vilazodone-d8 Usage And Synthesis
Description
Vilazodone-d8 is intended for use as an internal standard for the quantification of vilazodone by GC- or LC-MS. Vilazodone is a selective serotonin reuptake inhibitor (SSRI) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A (IC50s = 0.2 and 0.5 nM, respectively). It increases extracellular 5-HT in the rat ventral hippocampus and frontal cortex when administered intraperitoneally at doses of 1 and 3 mg/kg, respectively. Vilazodone (1 mg/kg, i.p.) decreases immobility in the forced swim test in both rats and mice. Formulations containing vilazodone have been used in the treatment of depression.
Chemical Properties
Off-White to Pale Yellow Solid
Uses
Labelled Vilazodone (V265000). It is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression. Antidepressant.
Uses
(Vilazodone-d8) Labelled Vilazodone. It is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression. Antidepressant.;Labeled Vilazodone, intended for use as an in
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Vilazodone-d8(1794789-93-7)Related Product Information
- 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-Benzofurancarboxylic acid
- Vilazodone Impurity 2
- Verazolonone related impurities
- Vilazodone Impurity 5
- Vilazodone related compound D
- VILAZODONE
- Vilazodone impurity 1
- 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxylic acid ethyl ester hydrochlorid
- Vilazodone Impurity 4
- Vilazodone iMpurity II
- Vilazodone Intermediate
- 5-(piperazin-1-yl)benzofuran-2-carboxylic acid
- Vilazodone Impurity 24
- 3-(4-Chloro-1-hydroxybutyl)-1H-indole-5-carbonitrile
- Vilazodone Impurity 3
- Vilazodone iMpurity C (N-Oxide)
- Vilazodone iMpurity
- Vilazodone Impurity 6